Biomarkers in multiple sclerosis

WJ Housley, D Pitt, DA Hafler - Clinical immunology, 2015 - Elsevier
Substantial effort has been made over the last six decades to identify biomarkers for multiple
sclerosis that can improve disease diagnosis, predict disease progression, and improve …

The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance

AS Doghish, O Elazazy, HH Mohamed… - … -Research and Practice, 2023 - Elsevier
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …

[HTML][HTML] MicroRNAs as biomarkers for CNS disease

P Rao, E Benito, A Fischer - Frontiers in molecular neuroscience, 2013 - frontiersin.org
For many neurological diseases, the efficacy and outcome of treatment depend on early
detection. Diagnosis is currently based on the detection of symptoms and neuroimaging …

Salivary microR‐153 and microR‐223 levels as potential diagnostic biomarkers of idiopathic Parkinson's disease

M Cressatti, L Juwara, JM Galindez… - Movement …, 2020 - Wiley Online Library
Background Parkinson's disease (PD) is the most common movement disorder among
adults, affecting 2% of the world population older than 65 years of age. No diagnostic …

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis

M Srinivasan, DK Lahiri - Expert opinion on therapeutic targets, 2015 - Taylor & Francis
Introduction: Advances in molecular pathogenesis suggest that the chronic inflammation is a
shared mechanism in the initiation and progression of multiple neurodegenerative diseases …

[HTML][HTML] Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies

KS Sheinerman, SR Umansky - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Many neurodegenerative diseases, such as Alzheimer's disease, Parkinson disease,
vascular and frontotemporal dementias, as well as other chronic neurological pathologies …

Cellular and molecular evidence of multiple sclerosis diagnosis and treatment challenges

Z Khan, GD Gupta, S Mehan - Journal of clinical medicine, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …

[HTML][HTML] Small non-coding RNAs as important players, biomarkers and therapeutic targets in multiple sclerosis: A comprehensive overview

E Piket, GY Zheleznyakova, L Kular, M Jagodic - Journal of autoimmunity, 2019 - Elsevier
Multiple sclerosis (MS) is a leading cause of progressive disability among young adults
caused by inflammation, demyelination and axonal loss in the central nervous system. Small …

[HTML][HTML] MicroRNA expression changes during interferon-beta treatment in the peripheral blood of multiple sclerosis patients

M Hecker, M Thamilarasan, D Koczan… - International journal of …, 2013 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNA molecules acting as post-transcriptional
regulators of gene expression. They are involved in many biological processes, and their …

TGF‐β regulation of encephalitogenic and regulatory T cells in multiple sclerosis

PW Lee, ME Severin… - European journal of …, 2017 - Wiley Online Library
Transforming growth factor beta (TGF‐β) is a pleiotropic cytokine that has been shown to
influence the differentiation and function of T cells. The role that TGF‐β plays in immune …