Antibiofilm activity of host defence peptides: complexity provides opportunities
Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …
[HTML][HTML] Reassessing the host defense peptide landscape
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
An overview of antimicrobial peptides and the latest advances in their development
Introduction: The recent dramatic increase in the incidence of antimicrobial resistance has
been recognized by organizations such as the United Nations and World Health …
been recognized by organizations such as the United Nations and World Health …
Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides
Antimicrobial peptides (AMPs), which combat bacterial infections by disrupting the bacterial
cell membrane or interacting with intracellular targets, are naturally produced by a number of …
cell membrane or interacting with intracellular targets, are naturally produced by a number of …
Biophysical investigations elucidating the mechanisms of action of antimicrobial peptides and their synergism
A Marquette, B Bechinger - Biomolecules, 2018 - mdpi.com
Biophysical and structural investigations are presented with a focus on the membrane lipid
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …
Computational antimicrobial peptide design and evaluation against multidrug-resistant clinical isolates of bacteria
D Nagarajan, T Nagarajan, N Roy, O Kulkarni… - Journal of Biological …, 2018 - ASBMB
There is a pressing need for new therapeutics to combat multidrug-and carbapenem-
resistant bacterial pathogens. This challenge prompted us to use a long short-term memory …
resistant bacterial pathogens. This challenge prompted us to use a long short-term memory …
The mechanisms of action of cationic antimicrobial peptides refined by novel concepts from biophysical investigations
C Aisenbrey, A Marquette, B Bechinger - Antimicrobial Peptides: Basics …, 2019 - Springer
Even 30 years after the discovery of magainins, biophysical and structural investigations on
how these peptides interact with membranes can still bear surprises and add new …
how these peptides interact with membranes can still bear surprises and add new …
[HTML][HTML] Antimicrobial activity of an artificially designed peptide against fish pathogens
RAH Bhat, VC Khangembam, D Thakuria, V Pant… - Microbiological …, 2022 - Elsevier
Antimicrobial peptides (AMPs) are considered alternatives to classical antibiotics and may
become an excellent candidate for tackling antimicrobial resistance in aquaculture …
become an excellent candidate for tackling antimicrobial resistance in aquaculture …
Perspectives on the antibiotic contamination, resistance, metabolomics, and systemic remediation
KK Sodhi, M Kumar, B Balan, AS Dhaulaniya… - SN Applied …, 2021 - Springer
Antibiotics have been regarded as the emerging contaminants because of their massive use
in humans and veterinary medicines and their persistence in the environment. The global …
in humans and veterinary medicines and their persistence in the environment. The global …
Structure and function in antimicrobial piscidins: histidine position, directionality of membrane insertion, and pH-dependent permeabilization
Piscidins are histidine-enriched antimicrobial peptides that interact with lipid bilayers as
amphipathic α-helices. Their activity at acidic and basic pH in vivo makes them promising …
amphipathic α-helices. Their activity at acidic and basic pH in vivo makes them promising …