Physiological protection against weight gain: evidence from overfeeding studies and future directions
J Lund, C Clemmensen - Philosophical Transactions of …, 2023 - royalsocietypublishing.org
Body weight is under physiological regulation. When body fat mass decreases, a series of
responses are triggered to promote weight regain by increasing food intake and decreasing …
responses are triggered to promote weight regain by increasing food intake and decreasing …
A critical update on the l eptin‐melanocortin system
The discovery of leptin in 1994 was an “eureka moment” in the field of neurometabolism that
provided new opportunities to better understand the central control of energy balance and …
provided new opportunities to better understand the central control of energy balance and …
Epigallocatechin gallate enhances sympathetic heart rate variability and decreases blood pressure in obese subjects: a randomized control trial
KT Wilasrusmee, C Sitticharoon, I Keadkraichaiwat… - Scientific Reports, 2024 - nature.com
This study aimed to investigate effects of epigallocatechin gallate (EGCG) on blood pressure
(BP) and autonomic nervous system, indicated by 5-min heart rate variability (HRV) …
(BP) and autonomic nervous system, indicated by 5-min heart rate variability (HRV) …
Rheumatic diseases and metabolism: where centre and periphery meet
M López, O Gualillo - Nature Reviews Rheumatology, 2024 - nature.com
Over the past few decades, the connection between metabolism and various inflammatory
and rheumatic diseases has been an area of active investigation. Nonetheless, the precise …
and rheumatic diseases has been an area of active investigation. Nonetheless, the precise …
βAR-mTOR-lipin1 pathway mediates PKA-RIIβ deficiency-induced adipose browning
B Wang, Z Hu, L Cui, M Zhao, Z Su, Y Jiang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Enhancing white adipose tissue (WAT) browning combats obesity. The RIIβ
subunit of cAMP-dependent protein kinase (PKA) is primarily expressed in the brain and …
subunit of cAMP-dependent protein kinase (PKA) is primarily expressed in the brain and …
Peripheral, central, and chemotherapy-induced neuropathic changes in pancreatic cancer
L Jiang, S Cai, Z Weng, S Zhang, SH Jiang - Trends in Neurosciences, 2024 - cell.com
In pancreatic cancer, significant alterations occur in the local nervous system, including
axonogenesis, neural remodeling, perineural invasion, and perineural neuritis. Pancreatic …
axonogenesis, neural remodeling, perineural invasion, and perineural neuritis. Pancreatic …
Immunomodulatory leptin receptor+ sympathetic perineurial barrier cells protect against obesity by facilitating brown adipose tissue thermogenesis
Adipose tissues (ATs) are innervated by sympathetic nerves, which drive reduction of fat
mass via lipolysis and thermogenesis. Here, we report a population of immunomodulatory …
mass via lipolysis and thermogenesis. Here, we report a population of immunomodulatory …
The Sympathetic‐Immune Milieu in Metabolic Health and Diseases: Insights from Pancreas, Liver, Intestine, and Adipose Tissues
W Ren, M Hua, F Cao, W Zeng - Advanced Science, 2024 - Wiley Online Library
Sympathetic innervation plays a crucial role in maintaining energy balance and contributes
to metabolic pathophysiology. Recent evidence has begun to uncover the innervation …
to metabolic pathophysiology. Recent evidence has begun to uncover the innervation …
Therapeutically Fine-Tuning Autonomic Nervous System to Treat Sepsis: A New Perspective on the Immunomodulatory Effects of Acupuncture
Recent studies have highlighted the immunomodulatory effects of acupuncture on sepsis
and proposed novel non-pharmacological or bioelectronic approaches to managing …
and proposed novel non-pharmacological or bioelectronic approaches to managing …