Food-grade titanium dioxide exposure exacerbates tumor formation in colitis associated cancer model

IM Urrutia-Ortega, LG Garduño-Balderas… - Food and Chemical …, 2016 - Elsevier
Colorectal cancer is the fourth worldwide cause of death and even if some dietary habits are
consider risk factors, the contribution of food additives including foodgrade titanium dioxide …

[HTML][HTML] The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Crypt Foci in Rats and the Apoptotic Effect of …

S Zorofchian Moghadamtousi, E Rouhollahi… - PloS one, 2015 - journals.plos.org
Annona muricata has been used in folk medicine for the treatment of cancer and tumors.
This study evaluated the chemopreventive properties of an ethyl acetate extract of A …

Gastroprotective activity of Annona muricata leaves against ethanol-induced gastric injury in rats via Hsp70/Bax involvement

SZ Moghadamtousi, E Rouhollahi… - Drug design …, 2014 - Taylor & Francis
The popular fruit tree of Annona muricata L.(Annonaceae), known as soursop and graviola,
is a widely distributed plant in Central and South America and tropical countries. Leaves of …

[HTML][HTML] Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer

B Refaat, AG El-Shemi, OA Kensara… - Journal of Experimental …, 2015 - Springer
Background Vitamin D3 and its analogues have recently been shown to enhance the anti-
tumour effects of 5-Fluorouracil (5-FU) both in vitro and in xenograft mouse model of colon …

Folate/vitamin B12 supplementation combats oxidative stress-associated carcinogenesis in a rat model of colon cancer

S Padmanabhan, MI Waly, V Taranikanti… - Nutrition and …, 2019 - Taylor & Francis
Folate and vitamin B12 deficiency is associated with depletion of the major intracellular
antioxidant glutathione, and oxidative stress is emerging as an etiological mechanism for …

[HTML][HTML] Evaluation of acute toxicity and gastroprotective activity of curcuma purpurascens BI. rhizome against ethanol-induced gastric mucosal injury in rats

E Rouhollahi, S Zorofchian Moghadamtousi… - … and Alternative medicine, 2014 - Springer
Background Curcuma purpurascens BI. is a medicinal plant from the Zingiberaceae family,
which is widely used as a spice and as folk medicine. The aim of the present study is to …

[HTML][HTML] In vivo acute toxicity evaluation and in vitro molecular mechanism study of antiproliferative activity of a novel indole Schiff base β-diiminato manganeseIII …

R Farghadani, M Seifaddinipour, J Rajarajeswaran… - PeerJ, 2019 - peerj.com
Breast cancer is the most frequently diagnosed cancer among women worldwide. Recently,
increasing attention has been paid to the anticancer effects of transition metal complexes of …

[HTML][HTML] Construing the biochemical and molecular mechanism underlying the in vivo and in vitro chemotherapeutic efficacy of ruthenium-baicalein complex in colon …

Y Wang, L Bian, T Chakraborty, T Ghosh… - … Journal of Biological …, 2019 - ncbi.nlm.nih.gov
In pursuit of a novel approach in colon cancer therapy, we explored the ability of ruthenium
baicalein complex to eradicate colon cancer by efficiently targeting various apoptotic …

Deciphering the biochemical and molecular mechanism underlying the in vitro and in vivo chemotherapeutic efficacy of ruthenium quercetin complex in colon cancer

S Roy, R Das, B Ghosh… - Molecular …, 2018 - Wiley Online Library
Flavonoids are the most investigated phytochemicals due to their pharmacological and
therapeutic activities. Their ability to chelate with metal ions has resulted in the emergence …

Bavachinin mitigates DMH induced colon cancer in rats by altering p53/Bcl2/BAX signaling associated with apoptosis

C Zhao, B Ghosh, T Chakraborty… - Biotechnic & …, 2021 - Taylor & Francis
Bavachinin is a flavanone obtained from the Chinese herb, Fructus Psoraleae. Flavonoids
and flavanones are recognized as cancer preventive agents. We investigated the anticancer …