Photoclick chemistry: a bright idea

BD Fairbanks, LJ Macdougall, S Mavila, J Sinha… - Chemical …, 2021 - ACS Publications
At its basic conceptualization, photoclick chemistry embodies a collection of click reactions
that are performed via the application of light. The emergence of this concept has had …

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

DP Murale, SC Hong, MM Haque, JS Lee - Proteome Science, 2016 - Springer
Protein-protein interactions (PPIs) trigger a wide range of biological signaling pathways that
are crucial for biomedical research and drug discovery. Various techniques have been used …

Systems for stimuli-controlled release: Materials and applications

M Bruneau, S Bennici, J Brendle, P Dutournie… - Journal of Controlled …, 2019 - Elsevier
The design and development of delivery controlled systems of molecules of interest has
attracted great interest over the last years. pH variation, light irradiation, temperature …

Self‐assembled nanomedicines for anticancer and antibacterial applications

L Zhou, T Qiu, F Lv, L Liu, J Ying… - Advanced Healthcare …, 2018 - Wiley Online Library
Self‐assembly strategies have been widely applied in the nanomedicine field, which provide
a convenient approach for building various structures for delivery carriers. When …

Photocrosslinking probes for capture of carbohydrate interactions

H Wu, J Kohler - Current opinion in chemical biology, 2019 - Elsevier
Glycan-mediated interactions are essential in many biological processes and regulate a
wide variety of cellular functions. However, characterizing these interactions is difficult …

Design, synthesis, and utility of defined molecular scaffolds

D Sato, Z Wu, H Fujita, JS Lindsey - Organics, 2021 - mdpi.com
A growing theme in chemistry is the joining of multiple organic molecular building blocks to
create functional molecules. Diverse derivatizable structures—here termed “scaffolds” …

Bio-related applications of porous organic frameworks (POFs)

H Zhang, G Li, C Liao, Y Cai, G Jiang - Journal of Materials Chemistry …, 2019 - pubs.rsc.org
Increasing attention has been given to the field of porous organic frameworks (POFs) due to
their unique properties, outstanding performance, and broad applications. Given their …

Photoswitchable CAR-T cell function in vitro and in vivo via a cleavable mediator

B Zhang, Y Wang, S Huang, J Sun, M Wang, W Ma… - Cell Chemical …, 2021 - cell.com
Chimeric antigen receptor (CAR)-T-based therapeutics are a breakthrough in cancer
treatment; however, they are hampered by constitutive activation, which leads to worrisome …

Gold (I)-mediated decaging or cleavage of propargylated peptide bond in aqueous conditions for protein synthesis and manipulation

M Jbara, E Eid, A Brik - Journal of the American Chemical Society, 2020 - ACS Publications
Chemists have been interested in the N-alkylation of a peptide bond because such a
modification alters the conformation of the amide bond, interferes with hydrogen bond …

Carnosic acid alleviates hyperlipidemia and insulin resistance by promoting the degradation of SREBPs via the 26S proteasome

Z Xie, X Wan, L Zhong, H Yang, P Li, X Xu - Journal of Functional Foods, 2017 - Elsevier
Carnosic acid (CA), from rosemary, a food additive used for long history in western
countries, reduces triglyceride, cholesterol and glucose levels. However, the detailed …