Abstract Background Rapid diagnostic tests (RDTs) are increasingly becoming a paradigm
for both clinical diagnosis of malaria infections and for estimating community parasite …

Non-human primates represent a valuable resource for testing potential vaccines
candidates and drugs for human use. Malaria remains one of the greatest burdens for the …

Background Reactive case detection could be a powerful tool in malaria elimination, as it
selectively targets transmission pockets. However, field operations have yet to demonstrate …

Background Malaria blood-stage infection length and intensity are important drivers of
disease and transmission; however, the underlying mechanisms of parasite growth and the …

We are developing a radiation attenuated Plasmodium falciparum sporozoite (PfSPZ)
malaria vaccine. An important step was to determine the minimum dose of irradiation …

The human malaria-Aotus monkey model has served the malaria research community since
its inception in 1966 at the Gorgas Memorial Laboratory (GML) in Panama. Spanning over …

Abstract Background The number of Plasmodium falciparum malaria cases around the world
has decreased substantially over the last 15 years, but with the spread of resistance against …

Neither GMP malaria antigens nor GMP vaccines have been compared for efficacy in
monkeys and humans. It is too risky to base categorical (go/no go) development decisions …

Background The long‐term effect of a PVC pipe nest‐box on the reproductive efficiency and
other life traits of an Aotus monkey‐breeding colony have not been characterized. Methods …

Severe anemia is the earliest and a frequently fatal complication of Plasmodium falciparum
infection. Here we describe Aotus infulatus as a primate model suitable to study this malaria …