Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Demystifying ecological connectivity for actionable spatial conservation planning

M Beger, A Metaxas, AC Balbar, JA McGowan… - Trends in ecology & …, 2022 - cell.com
Connectivity underpins the persistence of life; it needs to inform biodiversity conservation
decisions. Yet, when prioritising conservation areas and developing actions, connectivity is …

Genetic diversity loss in the Anthropocene

M Exposito-Alonso, TR Booker, L Czech, L Gillespie… - Science, 2022 - science.org
Anthropogenic habitat loss and climate change are reducing species' geographic ranges,
increasing extinction risk and losses of species' genetic diversity. Although preserving …

Conservation genetics as a management tool: The five best-supported paradigms to assist the management of threatened species

Y Willi, TN Kristensen, CM Sgrò… - Proceedings of the …, 2022 - National Acad Sciences
About 50 y ago, Crow and Kimura [An Introduction to Population Genetics Theory (1970)]
and Ohta and Kimura [Genet. Res. 22, 201–204 (1973)] laid the foundations of conservation …

Inbreeding depression explains killer whale population dynamics

M Kardos, Y Zhang, KM Parsons, H Kang… - Nature Ecology & …, 2023 - nature.com
Understanding the factors that cause endangered populations to either grow or decline is
crucial for preserving biodiversity. Conservation efforts often address extrinsic threats, such …

The critically endangered vaquita is not doomed to extinction by inbreeding depression

JA Robinson, CC Kyriazis, SF Nigenda-Morales… - Science, 2022 - science.org
In cases of severe wildlife population decline, a key question is whether recovery efforts will
be impeded by genetic factors, such as inbreeding depression. Decades of excess mortality …

Genetic diversity and IUCN Red List status

C Schmidt, S Hoban, M Hunter, I Paz‐Vinas… - Conservation …, 2023 - Wiley Online Library
Abstract The International Union for Conservation of Nature (IUCN) Red List is an important
and widely used tool for conservation assessment. The IUCN uses information about a …

The contribution of historical processes to contemporary extinction risk in placental mammals

AP Wilder, MA Supple, A Subramanian, A Mudide… - Science, 2023 - science.org
Species persistence can be influenced by the amount, type, and distribution of diversity
across the genome, suggesting a potential relationship between historical demography and …

Purging and accumulation of genetic load in conservation

N Dussex, HE Morales, C Grossen, L Dalén… - Trends in ecology & …, 2023 - cell.com
Our ability to assess the threat posed by the genetic load to small and declining populations
has been greatly improved by advances in genome sequencing and computational …

Functional genomic diversity is correlated with neutral genomic diversity in populations of an endangered rattlesnake

S Mathur, AJ Mason, GS Bradburd… - Proceedings of the …, 2023 - National Acad Sciences
Theory predicts that genetic erosion in small, isolated populations of endangered species
can be assessed using estimates of neutral genetic variation, yet this widely used approach …