Researchers from diverse backgrounds are converging on the view that human evolution
has been shaped by gene–culture interactions. Theoretical biologists have used population …

Hypohidrotic (anhidrotic) ectodermal dysplasia (HED) is a congenital syndrome
characterized by sparse hair, oligodontia, and reduced sweating. It is caused by mutations in …

Abstract Knowledge of genome-wide genealogies for thousands of individuals would
simplify most evolutionary analyses for humans and other species, but has remained …

The use of socially learned information (culture) is central to human adaptations. We
investigate the hypothesis that the process of cultural evolution has played an active …

We report a genome-wide association scan for facial features in∼ 6,000 Latin Americans.
We evaluated 14 traits on an ordinal scale and found significant association (P values< 5× …

The degree to which adaptation in recent human evolution shapes genetic variation remains
controversial. This is in part due to the limited evidence in humans for classic “hard selective …

An adaptive variant of the human Ectodysplasin receptor, EDARV370A, is one of the
strongest candidates of recent positive selection from genome-wide scans. We have …

Background The genetic bases of many complex phenotypes are still largely unknown,
mostly due to the polygenic nature of the traits and the small effect of each associated …

Shovel shape of upper incisors is a common characteristic in Asian and Native American
populations but is rare or absent in African and European populations. Like other common …

The availability of large-scale population genomic sequence data has resulted in an
explosion in efforts to infer the demographic histories of natural populations across a broad …