Citrate anticoagulation for continuous renal replacement therapy (CRRT) in patients with acute kidney injury admitted to the intensive care unit

A Davenport, A Tolwani - NDT plus, 2009 - academic.oup.com
Continuous forms of renal replacement therapy (CRRT) have become established as the
treatment of choice for supporting critically ill patients with acute kidney injury. Typically …

Is regional citrate anticoagulation the future of hemodialysis?

J Buturovic‐Ponikvar - Therapeutic Apheresis and Dialysis, 2016 - Wiley Online Library
Citrate has many characteristics of the ideal anticoagulant for hemodialysis. In addition to
immediate and complete anticoagulation in the dialysis circuit, citrate has important effects …

Uremic toxins and lipases in haemodialysis: a process of repeated metabolic starvation

B Stegmayr - Toxins, 2014 - mdpi.com
Severe kidney disease results in retention of uremic toxins that inhibit key enzymes for lipid
breakdown such as lipoprotein lipase (LPL) and hepatic lipase (HL). For patients in …

Regional citrate anticoagulation for hemodialysis: calcium-free vs. calcium containing dialysate-a randomized trial

J Buturovic-Ponikvar, S Cerne… - … Journal of Artificial …, 2008 - journals.sagepub.com
Background The majority of citrate protocols for hemodialysis (HD) use calcium (Ca)-free
dialysate, a limited number use dialysate with Ca, aiming to simplify the procedure. This …

Modified regional citrate anticoagulation is optimal for hemodialysis in patients at high risk of bleeding: a prospective randomized study of three anticoagulation …

T Lin, L Song, R Huang, Y Huang, S Tang, Q Lin… - BMC nephrology, 2019 - Springer
Background Recommended regular saline flushing presents clinical ineffectiveness for
hemodialysis (HD) patients at high risk of bleeding with heparin contraindication. Regional …

An evaluation of four modes of low-dose anticoagulation during intermittent haemodialysis

MSE Skagerlind, BG Stegmayr - European Journal of Clinical …, 2018 - Springer
Introduction Intensive care participants that need dialysis frequently suffer from increased
risk of bleeding. Standard intermittent haemodialysis (SHD) includes anticoagulation to …

Hemodialysis patients have signs of a chronic thrombotic burden

BG Stegmayr, LD Lundberg - BMC nephrology, 2024 - Springer
Background Cardiovascular diseases are the dominant cause of morbidity in hemodialysis
(HD) patients. Unless sufficient anticoagulation is used during HD, clotting may appear. The …

Treatment efficacy and safety during plasma exchange with citrate anticoagulation: a randomized study of 4 versus 15% citrate

M Antonic, J Gubensek, J Buturovic‐Ponikvar… - Artificial …, 2016 - Wiley Online Library
In plasma exchange (PE), contrary to dialysis, there is no ultrafiltration, and the volume of
anticoagulant contributes to volume overload of the patient and might also reduce PE …

Simplified citrate anticoagulation for CRRT without calcium replacement

M Broman, B Klarin, K SAnDIn, O Carlsson… - Asaio …, 2015 - journals.lww.com
Since 2012, citrate anticoagulation is the recommended anticoagulation strategy for
continuous renal replacement therapy (CRRT). The main drawback using citrate as …

Citrate Extended High Cut‐Off Hemodiafiltration for Renal Recovery in Patients With Multiple Myeloma

A Marn Pernat, B Medved, J Gubenšek… - Therapeutic …, 2016 - Wiley Online Library
We proposed a combination of convective and diffusive transport mechanisms as high cut‐
off (HCO) post‐dilution hemodiafiltration dialysis technique to optimize serum …