Inflammation is a key feature in the pathogenesis of sepsis and acute respiratory distress
syndrome (ARDS). Sepsis and ARDS continue to be associated with high mortality. A key …

Chronic obstructive pulmonary disease (COPD) is the most prevalent obstructive lung
disease worldwide characterized by decline in lung function. It is associated with airway …

Rationale: During acute lung injury (ALI), mechanical ventilation can aggravate inflammation
by promoting alveolar distension and cyclic recruitment–derecruitment. As an estimate of the …

Executive Summary The University of Vermont College of Medicine and the Vermont Lung
Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the Alpha-1 …

Objective: Neutrophilic inflammation plays a key role in the pathogenesis of acute
respiratory distress syndrome (ARDS) and acute lung injury (ALI). Positron emission …

Objectives: Regional tidal lung strain may trigger local inflammation during mechanical
ventilation, particularly when additional inflammatory stimuli are present. However, it is …

Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …

OBJECTIVE. The purpose of this review is to describe the current experimental and clinical
data regarding the fundamentals and applications of 18F-FDG PET during acute lung injury …

Abstract Changes in the mesolimbic dopamine (DA) system are implicated in a range of
neuropsychiatric conditions including addiction, depression and schizophrenia. Dysfunction …

Objective: The common denominator in most forms of ventilator-induced lung injury is an
intense inflammatory response mediated by neutrophils. PET with [18 F] fluoro-2-deoxy-D …