Genomic predictors of asthma phenotypes and treatment response

N Hernandez-Pacheco, M Pino-Yanes… - Frontiers in …, 2019 - frontiersin.org
Asthma is a complex respiratory disease considered as the most common chronic condition
in children. A large genetic contribution to asthma susceptibility is predicted by the clustering …

Recent trends in exhaled breath diagnosis using an artificial olfactory system

C Kim, IS Raja, JM Lee, JH Lee, MS Kang, SH Lee… - Biosensors, 2021 - mdpi.com
Artificial olfactory systems are needed in various fields that require real-time monitoring,
such as healthcare. This review introduces cases of detection of specific volatile organic …

Research progress of metabolomics in asthma

C Wang, S Jiang, S Zhang, Z Ouyang, G Wang, F Wang - Metabolites, 2021 - mdpi.com
Asthma is a highly heterogeneous disease, but the pathogenesis of asthma is still unclear. It
is well known that the airway inflammatory immune response is the pathological basis of …

Breathomics: review of sample collection and analysis, data modeling and clinical applications

M Khoubnasabjafari, MRA Mogaddam… - Critical Reviews in …, 2022 - Taylor & Francis
Metabolomics research is rapidly gaining momentum in disease diagnosis, on top of other
Omics technologies. Breathomics, as a branch of metabolomics is developing in various …

Update on metabolomic findings in COPD patients

J Gea, CJ Enríquez-Rodríguez… - ERJ Open …, 2023 - Eur Respiratory Soc
COPD is a heterogeneous disorder that shows diverse clinical presentations (phenotypes
and “treatable traits”) and biological mechanisms (endotypes). This heterogeneity implies …

Clinical metabolomics of exhaled breath condensate in chronic respiratory diseases

M Maniscalco, S Fuschillo, D Paris, A Cutignano… - Advances in clinical …, 2019 - Elsevier
Chronic respiratory diseases (CRDs) are complex multifactorial disorders involving the
airways and other lung structures. The development of reliable markers for an early and …

[HTML][HTML] The gut microbiome is a significant risk factor for future chronic lung disease

Y Liu, SM Teo, G Méric, HHF Tang, Q Zhu… - Journal of Allergy and …, 2023 - Elsevier
Background The gut-lung axis is generally recognized, but there are few large studies of the
gut microbiome and incident respiratory disease in adults. Objectives To investigate the …

An updated overview of metabolomic profile changes in chronic obstructive pulmonary disease

N Ran, Z Pang, Y Gu, H Pan, X Zuo, X Guan, Y Yuan… - Metabolites, 2019 - mdpi.com
Chronic obstructive pulmonary disease (COPD), a common and heterogeneous respiratory
disease, is characterized by persistent and incompletely reversible airflow limitation …

Untargeted metabolomics of human plasma reveal lipid markers unique to chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

S Nambiar, DBA Tan, B Clynick… - PROTEOMICS …, 2021 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is characterised by airway inflammation and
progressive airflow limitation, whereas idiopathic pulmonary fibrosis (IPF) is characterised …

Metabolomic analysis of respiratory epithelial lining fluid in patients with chronic obstructive pulmonary disease—a systematic review

K Pulik, K Mycroft, P Korczyński, AK Ciechanowicz… - Cells, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD), as the third leading cause of death among
adults, is a significant public health problem around the world. However, about 75% of …