Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease
H Abdala-Valencia, ME Coden… - Journal of leukocyte …, 2018 - academic.oup.com
Eosinophils play homeostatic roles in different tissues and are found in several organs at a
homeostatic baseline, though their tissue numbers increase significantly in development …
homeostatic baseline, though their tissue numbers increase significantly in development …
[HTML][HTML] Single-cell RNA-Seq of human esophageal epithelium in homeostasis and allergic inflammation
Inflammation of the esophageal epithelium is a hallmark of eosinophilic esophagitis (EoE),
an emerging chronic allergic disease. Herein, we probed human esophageal epithelial cells …
an emerging chronic allergic disease. Herein, we probed human esophageal epithelial cells …
Immunogenetic, Molecular and Microbiotic Determinants of Eosinophilic Esophagitis and Clinical Practice—A New Perspective of an Old Disease
A Kanikowska, S Hryhorowicz, AM Rychter… - International Journal of …, 2021 - mdpi.com
Eosinophilic oesophagitis (EoE) is a chronic, allergic disease associated with a T-
lymphocyte response inducing esophageal eosinophilic infiltration in the esophagus …
lymphocyte response inducing esophageal eosinophilic infiltration in the esophagus …
Impaired LRP6-TCF7L2 activity enhances smooth muscle cell plasticity and causes coronary artery disease
R Srivastava, J Zhang, G Go, A Narayanan, TP Nottoli… - Cell reports, 2015 - cell.com
Mutations in Wnt-signaling coreceptor LRP6 have been linked to coronary artery disease
(CAD) by unknown mechanisms. Here, we show that reduced LRP6 activity in LRP6 R611C …
(CAD) by unknown mechanisms. Here, we show that reduced LRP6 activity in LRP6 R611C …
Allergen‐specific B cell responses in oral immunotherapy‐induced desensitization, remission, and natural outgrowth in cow's milk allergy
Background Antigen‐specific memory B cells play a key role in the induction of
desensitization and remission to food allergens in oral immunotherapy and in the …
desensitization and remission to food allergens in oral immunotherapy and in the …
Epigenetic methylation in eosinophilic esophagitis: molecular ageing and novel biomarkers for treatment response
ET Jensen, CD Langefeld… - Clinical & …, 2020 - Wiley Online Library
Background Treatment failure in eosinophilic esophagitis (EoE) is common. We hypothesize
that DNA methylation differs between patients by treatment response to topical steroids (oral …
that DNA methylation differs between patients by treatment response to topical steroids (oral …
[PDF][PDF] Mechanisms of allergen-specific B cell tolerance in children with cow's milk-oral immunotherapy and natural outgrowth of milk allergy
Antigen-speci c memory B cells play a key role in the induction of immune tolerance to food
allergens and clinical healing. Here, we characterized the role of allergen-speci c B cells in …
allergens and clinical healing. Here, we characterized the role of allergen-speci c B cells in …