[HTML][HTML] Drug repurposing in medical mycology: Identification of compounds as potential antifungals to overcome the emergence of multidrug-resistant fungi

L Peyclit, H Yousfi, JM Rolain, F Bittar - Pharmaceuticals, 2021 - mdpi.com
Immunodepression, whether due to HIV infection or organ transplantation, has increased
human vulnerability to fungal infections. These conditions have created an optimal …

Potentiating activity of Norfloxacin by synthetic chalcones against NorA overproducing Staphylococcus aureus

ALAB Leal, PT da Silva, MN da Rocha… - Microbial …, 2021 - Elsevier
Staphylococcus aureus is responsible for a series of infections occurring in both human and
animal hosts. S. aureus SA1199B is a strain resistant to hydrophilic fluoroquinolone due to …

Bibliometric analysis and thematic review of Candida pathogenesis: Fundamental omics to applications as potential antifungal drugs and vaccines

SJ Lim, ND Muhd Noor, S Sabri… - Medical …, 2024 - academic.oup.com
Invasive candidiasis caused by the pathogenic Candida yeast species has resulted in
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …

Antibacterial activity of paroxetine against Staphylococcus aureus and possible mechanisms of action

VPF Cabral, DS Rodrigues, AD Barbosa… - Future …, 2023 - Taylor & Francis
Aim: To evaluate the antibacterial activity of paroxetine alone and associated with oxacillin
against isolates of methicillin-sensitive and-resistant Staphylococcus aureus. Materials & …

[HTML][HTML] Etomidate affects spatial learning and memory and neuronal apoptosis of rats via MAPK/ERK pathway

S Xie, X Li, H Xie - American Journal of Translational Research, 2022 - ncbi.nlm.nih.gov
Objective: To observe the effect of etomidate on spatial learning and memory and neuronal
apoptosis in rats of different ages. Methods: The rats of different ages were divided into 3 …

[HTML][HTML] Globospiramine Exhibits Inhibitory and Fungicidal Effects against Candida albicans via Apoptotic Mechanisms

JAH Manzano, S Brogi, V Calderone, APG Macabeo… - Biomolecules, 2024 - mdpi.com
Candidiasis is considered an emerging public health concern because of the occurrence of
drug-resistant Candida strains and the lack of an available structurally diverse antifungal …

Sertraline has in vitro activity against both mature and forming biofilms of different Candida species

DS Rodrigues, VPF Cabral… - Journal of Medical …, 2023 - microbiologyresearch.org
Candida spp. infections are a serious health problem, especially in patients with risk factors.
The acquisition of resistance, often associated with biofilm production, makes treatment …

Mangiferin potentiates the activity of antifungal agents against fluconazole-resistant Candida spp.

TL Ferreira, AC Leitão, LJ da Silva… - Future …, 2024 - Taylor & Francis
Aim: To evaluate the antifungal activity of mangiferin against Candida spp. resistant to
fluconazole. Materials & methods: The antifungal activity of mangiferin was assessed using …

Biosurfactant complexed with arginine has antibiofilm activity against methicillin-resistant Staphylococcus aureus

FD Dias Barroso, LJ da Silva, HA Queiroz… - Future …, 2024 - Taylor & Francis
Aim: The present study investigated the antimicrobial effectiveness of a rhamnolipid
complexed with arginine (RLMIX_Arg) against planktonic cells and biofilms of methicillin …

Sertraline Has Fungicidal Activity Against Candida Spp. and Acts by Inhibiting Membrane and Cell Wall Biosynthesis

DS Rodrigues, VPF Cabral, AD Barbosa… - Future …, 2023 - Taylor & Francis
Aim: Our study evaluated the activity of sertraline (SER) alone and associated with
antifungal drugs in planktonic Candida spp. strains, and investigated its mechanism of …