Anti-hepatocellular carcinoma biomolecules: molecular targets insights
This report explores the available curative molecules directed against hepatocellular
carcinoma (HCC). Limited efficiency as well as other drawbacks of existing molecules led to …
carcinoma (HCC). Limited efficiency as well as other drawbacks of existing molecules led to …
Anti-obesity effects of capsaicin and the underlying mechanisms: A review
Obesity and overweight have become serious health problems in the world and are linked to
a variety of metabolic disorders. Phytochemicals with a weight-loss effect have been widely …
a variety of metabolic disorders. Phytochemicals with a weight-loss effect have been widely …
Capsaicin inhibits proliferation and induces apoptosis in breast cancer by down-regulating FBI-1-mediated NF-κB pathway
M Chen, C Xiao, W Jiang, W Yang, Q Qin… - Drug Design …, 2021 - Taylor & Francis
Background As a natural compound extracted from a variety of hot peppers, capsaicin has
drawn increasing attention to its anti-cancer effects against multiple human cancers …
drawn increasing attention to its anti-cancer effects against multiple human cancers …
The effects of capsaicin on gastrointestinal cancers
GDA Popescu, C Scheau, IA Badarau, MD Dumitrache… - Molecules, 2020 - mdpi.com
Gastrointestinal (GI) cancers are a group of diseases with very high positions in the ranking
of cancer incidence and mortality. While they show common features regarding the …
of cancer incidence and mortality. While they show common features regarding the …
Capsaicin targets lipogenesis in HepG2 cells through AMPK activation, AKT inhibition and PPARs regulation
A Bort, BG Sánchez, PA Mateos-Gómez… - International journal of …, 2019 - mdpi.com
Obesity, a major risk factor for chronic diseases such as type 2 diabetes (T2D), represents a
serious primary health problem worldwide. Dietary habits are of special interest to prevent …
serious primary health problem worldwide. Dietary habits are of special interest to prevent …
Melatonin suppresses NLRP3 inflammasome activation via TLR4/NF-κB and P2X7R signaling in high-fat diet-induced murine NASH model
M Saha, K Manna, K Das Saha - Journal of Inflammation Research, 2022 - Taylor & Francis
Background NLRP3 inflammasome activation plays a critical role in mediating inflammation
and NASH (non-alcoholic steatohepatitis) progression that ultimately leads to cirrhosis and …
and NASH (non-alcoholic steatohepatitis) progression that ultimately leads to cirrhosis and …
TRPV1 activation by capsaicin mediates glucose oxidation and ATP production independent of insulin signalling in mouse skeletal muscle cells
Background: Insulin resistance (IR), a key characteristic of type 2 diabetes (T2DM), is
manifested by decreased insulin-stimulated glucose transport in target tissues. Emerging …
manifested by decreased insulin-stimulated glucose transport in target tissues. Emerging …
Capsaicin: effects on the pathogenesis of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most frequent cancers, and to date, there
have been very few drugs available that can improve survival, the most well-known being …
have been very few drugs available that can improve survival, the most well-known being …
Modulating effects of capsaicin on glucose homeostasis and the underlying mechanism
Abnormal glucose homeostasis is linked to a variety of metabolic syndromes, such as insulin
resistance, obesity, type-2 diabetes mellitus, hypertension and cardiovascular diseases …
resistance, obesity, type-2 diabetes mellitus, hypertension and cardiovascular diseases …
Advances in understanding and harnessing the molecular regulatory mechanisms of vegetable quality
L Gao, N Hao, T Wu, J Cao - Frontiers in Plant Science, 2022 - frontiersin.org
The quality of vegetables is facing new demands in terms of diversity and nutritional health.
Given the improvements in living standards and the quality of consumed products …
Given the improvements in living standards and the quality of consumed products …