The first steps towards establishing xenografts in zebrafish embryos were performed by Lee
et al., 2005 and Haldi et al., 2006, paving the way for studying human cancers using this …

Abstract A homogeneous polysaccharide, EJP90-1, was isolated from the leaves of E.
japonica by hot water extraction in this study. EJP90-1 (7702 Da) was a …

Inherited noncoding genetic variants confer significant disease susceptibility to childhood
acute lymphoblastic leukemia (ALL) but the molecular processes linking germline …

Zebrafish offer a powerful vertebrate model for studies of development and disease. The
major advantages of this model include the possibilities of conducting reverse and forward …

Only half of patients with relapsed B-cell precursor (BCP) acute lymphoblastic leukemia
(ALL) currently survive with standard treatment protocols. Predicting individual patient …

The enzymes that belong to the aldehyde dehydrogenase family are expressed in a variety
of cells; yet activity of their main members characterizes stem cells, both normal and …

Leukemia is a type of blood cancer characterized by high genetic heterogeneity and fatality.
While chemotherapy remains the primary form of treatment for leukemia, its effectiveness …

Glioblastoma and neuroblastoma are the most common central nervous system malignant
tumors in adult and pediatric populations. Both are associated with poor survival. These …

The present study aimed to determine whether 18 F‑FDG PET/CT performed before and/or
after allogeneic hematopoietic stem cell transplantation (allo‑HSCT) can predict clinical …

Background: Zebrafish (Danio rerio) is a vertebrate that has become a popular alternative
model for the cellular and molecular study of human tumors and for drug testing and …