Experimental research is critical for advancing medical knowledge and enhancing patient
outcomes, including in vitro and in vivo preclinical assessments. Platelet-rich fibrin (PRF) is …

Establishing animal models with critical size defects (CSDs) is critical for conducting
experimental investigations engineering of bone tissue regeneration. Currently, a …

This study aimed to evaluate the efficacy of calcium carbonate nanoparticles (CCNPs) to
induce new bone formation in a critical size segmental bone defect in rabbit's radius when …

Platelet-rich fibrin, a classical autologous-derived bioactive material, consists of a fibrin
scaffold and its internal loading of growth factors, platelets, and leukocytes, with the gradual …

Simple Summary Bone tissue engineering is one of the most promising approaches for the
restoration of large bone defects. Nevertheless, to date, several disadvantages limit its use …

This systematic review evaluated the potential utility of platelet-rich fibrin (PRF) in bone
repair in animals. The question is: can the use of PRF in bone defects in healthy rats induce …

Platelet-rich fibrin (PRF) is a protein matrix with growth factors and immune cells extracted
from venous blood via centrifugation. Previous studies proved it a beneficial biomaterial for …

In orthopedics, the repair of bone defects remains challenging. In previous research reports,
magnesium phosphate cements (MPCs) were widely used because of their excellent …

The study presents a novel approach to bone regeneration using bioactive nanocomposites.
The research focuses on creating hydroxyapatite (HAp) and zinc oxide (ZnO) …

Materials and Methods: Twenty rabbits were used in this investigation, and they were
divided into four groups based on the test observation period (3, 7, 21, and 28 days) …