Coronary microvascular dysfunction

F Vancheri, G Longo, S Vancheri, M Henein - Journal of Clinical …, 2020 - mdpi.com
Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies

JM Wardlaw, H Benveniste… - Annual Review of …, 2022 - annualreviews.org
Cerebral small vessel disease (SVD) is highly prevalent and a common cause of ischemic
and hemorrhagic stroke and dementia, yet the pathophysiology is poorly understood. Its …

Cerebral vessels: an overview of anatomy, physiology, and role in the drainage of fluids and solutes

N Agarwal, RO Carare - Frontiers in neurology, 2021 - frontiersin.org
The cerebral vasculature is made up of highly specialized structures that assure constant
brain perfusion necessary to meet the very high demand for oxygen and glucose by neurons …

Cognition in stroke rehabilitation and recovery research: Consensus-based core recommendations from the second Stroke Recovery and Rehabilitation Roundtable

MW McDonald, SE Black, DA Copland… - … Journal of Stroke, 2019 - journals.sagepub.com
Cognitive impairment is an important target for rehabilitation as it is common following
stroke, is associated with reduced quality of life and interferes with motor and other types of …

Small‐vessel disease in the heart and brain: current knowledge, unmet therapeutic need, and future directions

C Berry, N Sidik, AC Pereira, TJ Ford… - Journal of the …, 2019 - Am Heart Assoc
Methods We undertook a literature search for original research articles including information
on SVD in both heart and brain. The search used PubMed and covered the period January …

Image processing approaches to enhance perivascular space visibility and quantification using MRI

F Sepehrband, G Barisano, N Sheikh-Bahaei… - Scientific reports, 2019 - nature.com
Imaging the perivascular spaces (PVS), also known as Virchow-Robin space, has significant
clinical value, but there remains a need for neuroimaging techniques to improve mapping …

The ageing central nervous system in multiple sclerosis: the imaging perspective

M Filippi, P Preziosa, F Barkhof, O Ciccarelli… - Brain, 2024 - academic.oup.com
The interaction between ageing and multiple sclerosis is complex and carries significant
implications for patient care. Managing multiple sclerosis effectively requires an …

Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer's disease

CD Morrone, R Raghuraman, SA Hussaini… - Molecular …, 2023 - Springer
Failed proteostasis is a well-documented feature of Alzheimer's disease, particularly,
reduced protein degradation and clearance. However, the contribution of failed proteostasis …

Vascular cognitive impairment and HIV-associated neurocognitive disorder: a new paradigm

LA Cysique, BJ Brew - Journal of neurovirology, 2019 - Springer
In this review, we propose that vascular cognitive impairment (VCI), with relevance for the
global HIV population, is fundamentally and clinically linked to the persistence of mild forms …

Trained immunity characteristics are associated with progressive cerebral small vessel disease

MP Noz, A Ter Telgte, K Wiegertjes, LAB Joosten… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Cerebral small vessel disease (cSVD) is the major vascular
cause of cognitive decline and dementia. The pathogenesis of cSVD remains largely …