Bridging tissue repair and epithelial carcinogenesis: epigenetic memory and field cancerization

C Levra Levron, L Elettrico, C Duval… - Cell Death & …, 2024 - nature.com
The epigenome coordinates spatial-temporal specific gene expression during development
and in adulthood, for the maintenance of homeostasis and upon tissue repair. The upheaval …

[HTML][HTML] Fusion genes in pancreatic tumors

A Gkountakos, AD Singhi, CB Westphalen, A Scarpa… - Trends in Cancer, 2024 - cell.com
Gene fusions and rearrangements play a crucial role in tumor biology. They are rare events
typically detected in KRAS wild-type (WT) pancreatic tumors. Their identification can inform …