Inflammatory bowel disease (IBD) is a collective term for inflammatory diseases including
Crohn's disease and ulcerative colitis. Toll-like receptor 4 (TLR4) is thought to play a key …

Jatrorrhizine, an isoquinoline alkaloid, is a bioactive metabolite in common medicinal plants,
such as Berberis vernae Schneid., Tinospora sagittata (Oliv.) Gagnep. and Coptis chinensis …

Abstract Berberine (BBR), a naturally-occurring isoquinoline alkaloid isolated from several
Chinese herbal medicines, has been widely used for the treatment of dysentery and colitis …

Alkaloids are nitrogen-containing natural products found in bacteria, fungi, animals, and
plants with complex and diverse structures. The widespread distribution of alkaloids along …

Medicinal plants are traditionally used in Mexico to treat diseases such as cancer. The
present study aimed to evaluate the cytotoxic, antioxidant, and anti-hemolytic activity of 15 …

Cancer is the second most fatal disease worldwide, with colon cancer being the third most
prevalent and fatal form of cancer in several Western countries. The risk of acquisition of …

Lipid-lowering therapy is an important tool for the treatment of lipid metabolic diseases,
which are increasing in prevalence. However, the failure of conventional lipid-lowering …

Background Berberine (BBR) has been widely used to treat non-alcoholic fatty liver disease
(NAFLD). The metabolites of BBR were believed to contribute significantly to its …

Berberine (BBR) is an effective drug against liver fibrosis (LF). Autophagy is involved in the
pathogenesis of LF; however, the mechanism linking BBR to autophagy in LF remains …

Background Nanomedicine has evolved as precision medicine in novel therapeutic
approach of cancer management. The present study investigated the efficacy of biogenic …