Neuroinflammation (NF) is defined as the activation of brain glial cells that are found in
neurodegenerative diseases including Alzheimer's disease (AD). It has been known that an …

Major alterations in metabolism occur during pregnancy enabling the mother to provide
adequate nutrients to support infant development, affecting birth weight (BW) and potentially …

Chronic inflammation has been implicated in the pathophysiology of major depressive
disorder (MDD). Activating the resolution of inflammation through ω-3 fatty acid …

The protein Major Facilitator Superfamily Domain containing 2A (MFSD2a) was recently
described as the primary carrier for docosahexaenoic acid (DHA) into the brain. Alzheimer's …

Docosahexaenoic acid (DHA) is highly enriched in the brain, and is essential for normal
brain development and function. However, evidence suggests that currently used …

The blood brain barrier is a chemical and physical interface that separates the central
nervous system from systemic blood circulation. Dysfunction of the blood brain barrier is …

BACKGROUND Nutritional modulations may be considered a strategy to protect mental
health. Neuronal homeostasis is highly dependent on the availability of glucose, which …

Our knowledge of cerebral metabolism is shifting towards an understanding and
appreciation of non-neuronal and non-glucose contributions to meeting the brains high …

The blood-brain barrier (BBB) comprises the microvasculature network within the brain and
has a critical role in maintaining the barrier between the brain tissue and the blood. Proper …

Immunometabolism is fueling breakthroughs across oncology, infection control, and
inflammation research. It is appreciated that CD8 T cells are important players in all of the …