MicroRNA-based therapeutics in central nervous system injuries

P Sun, DZ Liu, GC Jickling… - Journal of Cerebral …, 2018 - journals.sagepub.com
Central nervous system (CNS) injuries, such as stroke, traumatic brain injury (TBI) and
spinal cord injury (SCI), are important causes of death and long-term disability worldwide …

Sex differences in the brain: Implications for behavioral and biomedical research

E Choleris, LAM Galea, F Sohrabji, KM Frick - … & Biobehavioral Reviews, 2018 - Elsevier
Biological differences between males and females are found at multiple levels. However,
females have too often been under-represented in behavioral neuroscience research, which …

Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice

H Zhang, J Wu, J Wu, Q Fan, J Zhou, J Wu… - Journal of …, 2019 - Springer
Background Accumulating evidence shows that microRNA-210 (miR-210) holds great
promise to improve angiogenesis for brain tissue repair after cerebral ischemia. However …

A systematic review of the research progress of non-coding RNA in neuroinflammation and immune regulation in cerebral infarction/ischemia-reperfusion injury

K Yang, L Zeng, A Ge, S Wang, J Zeng, X Yuan… - Frontiers in …, 2022 - frontiersin.org
Cerebral infarction/ischemia-reperfusion injury is currently the disease with the highest
mortality and disability rate of cardiovascular disease. Current studies have shown that …

Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease

H Geekiyanage, GA Jicha, PT Nelson, C Chan - Experimental neurology, 2012 - Elsevier
There is an urgent need to identify non-invasive biomarkers for the detection of sporadic
Alzheimer's disease (AD). We previously studied microRNAs (miRNAs) in AD autopsy brain …

MicroRNA: relevance to stroke diagnosis, prognosis, and therapy

H Mirzaei, F Momeni, L Saadatpour… - Journal of cellular …, 2018 - Wiley Online Library
Stroke is a life‐threatening disease that accounts for a considerable burden of mortality in
both developing and developed world. Identification of specific biomarkers for stroke and its …

MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy

B Li, C Dasgupta, L Huang, X Meng… - Cellular & Molecular …, 2020 - nature.com
Neuroinflammation is a major contributor to secondary neuronal injury that accounts for a
significant proportion of final brain cell loss in neonatal hypoxic-ischemic encephalopathy …

The role of microRNAs in human diseases

KU Tüfekci, MG Öner, RLJ Meuwissen… - … : MicroRNA biology and …, 2014 - Springer
About 20 years have passed since the discovery of the first microRNA (miRNA) and by now
microRNAs are implicated in a variety of physiological and pathological processes. Since …

[HTML][HTML] Emerging roles of microRNAs in ischemic stroke: as possible therapeutic agents

SE Khoshnam, W Winlow, Y Farbood… - Journal of …, 2017 - ncbi.nlm.nih.gov
Stroke is one of the leading causes of death and physical disability worldwide. The
consequences of stroke injuries are profound and persistent, causing in considerable …

Crosstalk of astrocytes and other cells during ischemic stroke

T He, GY Yang, Z Zhang - Life, 2022 - mdpi.com
Stroke is a leading cause of death and long-term disability worldwide. Astrocytes structurally
compose tripartite synapses, blood–brain barrier, and the neurovascular unit and perform …