Classical dynamical density functional theory: from fundamentals to applications

M te Vrugt, H Löwen, R Wittkowski - Advances in Physics, 2020 - Taylor & Francis
Classical dynamical density functional theory (DDFT) is one of the cornerstones of modern
statistical mechanics. It is an extension of the highly successful method of classical density …

Liposome and immune system interplay: Challenges and potentials

F Zahednezhad, M Saadat, H Valizadeh… - Journal of Controlled …, 2019 - Elsevier
Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery.
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …

Power functional theory for many-body dynamics

M Schmidt - Reviews of Modern Physics, 2022 - APS
The rich and diverse dynamics of particle-based systems ultimately originates from the
coupling of their degrees of freedom via internal interactions. To arrive at a tractable …

Mechanistic understanding of protein Corona formation around nanoparticles: old puzzles and new insights

K Nienhaus, GU Nienhaus - Small, 2023 - Wiley Online Library
Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …

In vivo protein corona on nanoparticles: does the control of all material parameters orient the biological behavior?

N Singh, C Marets, J Boudon, N Millot, L Saviot… - Nanoscale …, 2021 - pubs.rsc.org
Nanomaterials have a huge potential in research fields from nanomedicine to medical
devices. However, surface modifications of nanoparticles (NPs) and thus of their …

Understanding the interaction of polyelectrolyte architectures with proteins and biosystems

K Achazi, R Haag, M Ballauff… - Angewandte Chemie …, 2021 - Wiley Online Library
The counterions neutralizing the charges on polyelectrolytes such as DNA or heparin may
dissociate in water and greatly influence the interaction of such polyelectrolytes with …

Effects of social distancing and isolation on epidemic spreading modeled via dynamical density functional theory

M Te Vrugt, J Bickmann, R Wittkowski - Nature communications, 2020 - nature.com
For preventing the spread of epidemics such as the coronavirus disease COVID-19, social
distancing and the isolation of infected persons are crucial. However, existing reaction …

[HTML][HTML] Nanoparticles for biomedical applications: exploring and exploiting molecular interactions at the nano-bio interface

K Nienhaus, H Wang, GU Nienhaus - Materials Today Advances, 2020 - Elsevier
Nanomaterials have high potential as powerful tools for nanomedicine in a wide range of
most promising applications as highly specific devices for diagnosis and therapy. Yet …

A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies

B Youden, R Jiang, AJ Carrier, MR Servos, X Zhang - ACS nano, 2022 - ACS Publications
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …

Hemolytic activity of nanoparticles as a marker of their hemocompatibility

S Yedgar, G Barshtein, A Gural - Micromachines, 2022 - mdpi.com
The potential use of nanomaterials in medicine offers opportunities for novel therapeutic
approaches to treating complex disorders. For that reason, a new branch of science, named …