Cell-Based Therapies for the Treatment of Traumatic Brain Injury: Promises and Trajectories

KJ Habashy, S Omais, B Haupt, AM Sonabend… - Biologics, 2024 - mdpi.com
Traumatic Brain Injury (TBI) is a debilitating condition that poses a significant public health
concern. Historically linked to motor vehicle accidents, the epidemiology of TBI has evolved …

A multicenter validation of the modified brain injury guidelines: Are they safe and effective?

AD Khan, J Lee, K Galicia, JD Billings… - Journal of trauma and …, 2022 - journals.lww.com
BACKGROUND The modified Brain Injury Guidelines (mBIG) are an algorithm for treating
patients with traumatic brain injury and intracranial hemorrhage by which selected patients …

Optimal management of the geriatric trauma patient

M Farrell, P Kamat, RD Barraco - Current Surgery Reports, 2023 - Springer
Abstract Purpose of Review As our population continues to age, the proportion of geriatric
patients continues to rapidly increase. As a result, age-specific recommendations in the …

First steps toward a BIG change: A pilot study to implement the Brain Injury Guidelines across a 24-hospital system

AB Kay, SA Malone, JR Bledsoe, S Majercik… - The American Journal of …, 2023 - Elsevier
Abstract Introduction The modified Brain Injury Guidelines (mBIG) support a subset of low-
risk patients to be managed without repeat head computed tomography (RHCT) …

Committee on Surgical Combat Casualty Care position statement: Neurosurgical capability for the optimal management of traumatic brain injury during deployed …

JM Gurney, MD Tadlock, BA Dengler… - Journal of Trauma …, 2023 - journals.lww.com
BACKGROUND Experiences over the last three decades of war have demonstrated a high
incidence of traumatic brain injury (TBI) resulting in a persistent need for a neurosurgical …

Clinical Best Practice Integration (cBPI): a dynamic model for increasing adherence to evidence-based practice

TR Fowles, AJ Knighton, HL Carmichael… - Quality Management …, 2023 - journals.lww.com
Implementing evidence-based clinical practice with high adherence remains pivotal to
Intermountain Health's vision: helping people live the healthiest lives possible. To …

Key Findings on Computed Tomography of the Head That Predict Death or the Need for Neurosurgical Intervention From Traumatic Brain Injury

S Noorbakhsh, M Keirsey, A Hess… - The American …, 2024 - journals.sagepub.com
Background Traumatic brain injury (TBI) requires rapid management to avoid secondary
injury or death. This study evaluated if a simple schema for quickly interpreting CT head …

[HTML][HTML] The Brain Injury Guidelines (BIG) and emergency department observation and admission rates: A retrospective cohort study

LT Southerland, A Alnemer, C Laufenberg… - The American Journal of …, 2024 - Elsevier
Abstract Background Emergency Department (ED) Observation Units (OU) can provide safe,
effective care for low risk patients with intracranial hemorrhages. We compared current ED …

Implementation of the Modified Brain Injury Guidelines Might Be Feasible and Cost-Effective Even in a Nontrauma Hospital

KL Krause, A Brown, J Michael, M Mercurio, S Wo… - World Neurosurgery, 2024 - Elsevier
Introduction The modified Brain Injury Guidelines (mBIG) provide a framework to stratify
traumatic brain injury (TBI) patients based on clinical and radiographic factors in level 1 and …

[HTML][HTML] Identification and management of low-risk isolated traumatic brain injury patients initially treated at a rural level IV trauma center

RV Nene, B Corbett, G Lambert, AM Smith… - The American Journal of …, 2024 - Elsevier
Abstract Study Objective Our goal was to determine if low-risk, isolated mild traumatic brain
injury (TBI) patients who were initially treated at a rural emergency department may have …