[HTML][HTML] WormBase ParaSite− a comprehensive resource for helminth genomics
The number of publicly available parasitic worm genome sequences has increased
dramatically in the past three years, and research interest in helminth functional genomics is …
dramatically in the past three years, and research interest in helminth functional genomics is …
Schistosomiasis—from immunopathology to vaccines
DP McManus, R Bergquist, P Cai… - Seminars in …, 2020 - Springer
Schistosomiasis (bilharzia) is a neglected tropical disease caused by trematode worms of
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …
Comparative genomics of the major parasitic worms
Nature genetics, 2019 - nature.com
Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating
chronic infections of humans and animals, decimate crop production and are a major …
chronic infections of humans and animals, decimate crop production and are a major …
FASconCAT-G: extensive functions for multiple sequence alignment preparations concerning phylogenetic studies
Background Phylogenetic and population genetic studies often deal with multiple sequence
alignments that require manipulation or processing steps such as sequence concatenation …
alignments that require manipulation or processing steps such as sequence concatenation …
The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution
K Cwiklinski, JP Dalton, PJ Dufresne, J La Course… - Genome biology, 2015 - Springer
Abstract Background The liver fluke Fasciola hepatica is a major pathogen of livestock
worldwide, causing huge economic losses to agriculture, as well as 2.4 million human …
worldwide, causing huge economic losses to agriculture, as well as 2.4 million human …
Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?
R Bergquist, J Utzinger, J Keiser - Infectious diseases of poverty, 2017 - Springer
The current approach of morbidity control of schistosomiasis, a helminth disease of poverty
with considerable public health and socioeconomic impact, is based on preventive …
with considerable public health and socioeconomic impact, is based on preventive …
Immunomodulation by helminth parasites: defining mechanisms and mediators
Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …
models, strongly indicate that helminth parasitic infections can confer protection from …
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor
B Everts, L Hussaarts, NN Driessen… - Journal of Experimental …, 2012 - rupress.org
Omega-1, a glycosylated T2 ribonuclease (RNase) secreted by Schistosoma mansoni eggs
and abundantly present in soluble egg antigen, has recently been shown to condition …
and abundantly present in soluble egg antigen, has recently been shown to condition …
Hybridizations within the genus Schistosoma: implications for evolution, epidemiology and control
E Leger, JP Webster - Parasitology, 2017 - cambridge.org
Hybridization of parasites is an emerging public health concern in our changing world.
Hybridization and introgression in parasites and pathogens can have major impacts on the …
Hybridization and introgression in parasites and pathogens can have major impacts on the …
Cellular and chemokine-mediated regulation in schistosome-induced hepatic pathology
In hepatic schistosomiasis, pathology arises when schistosome eggs become lodged in the
host liver, evoking an interleukin 4 (IL-4)-and IL-13-mediated dominant CD4+ Th2 immune …
host liver, evoking an interleukin 4 (IL-4)-and IL-13-mediated dominant CD4+ Th2 immune …