EBV persistence—introducing the virus

DA Thorley-Lawson - Epstein Barr Virus Volume 1: One Herpes Virus …, 2015 - Springer
Persistent infection by EBV is explained by the germinal center model (GCM) which provides
a satisfying and currently the only explanation for EBVs disparate biology. Since the GCM …

The EBNA3 family: two oncoproteins and a tumour suppressor that are central to the biology of EBV in B cells

MJ Allday, Q Bazot, RE White - Epstein Barr Virus Volume 2: One Herpes …, 2015 - Springer
Epstein-Barr virus nuclear antigens EBNA3A EBNA3A, EBNA3B EBNA3B and EBNA3C
EBNA3C are a family of three large latency-associated proteins expressed in B cells …

Defective T‐cell control of Epstein–Barr virus infection in multiple sclerosis

MP Pender, PA Csurhes, JM Burrows… - Clinical & …, 2017 - Wiley Online Library
Mounting evidence indicates that infection with Epstein–Barr virus (EBV) has a major role in
the pathogenesis of multiple sclerosis (MS). Defective elimination of EBV‐infected B cells by …

Unraveling the Aurora kinase A and Epstein-Barr nuclear antigen 1 axis in Epstein Barr virus associated gastric cancer

N Varshney, S Murmu, B Baral, D Kashyap, S Singh… - Virology, 2023 - Elsevier
Aurora kinase A (AURKA) is one of the crucial cell cycle regulators associated with gastric
cancer. Here, we explored Epstein Barr Virus-induced gastric cancer progression through …

Extinct type of human parvovirus B19 persists in tonsillar B cells

L Pyöriä, M Toppinen, E Mäntylä, L Hedman… - Nature …, 2017 - nature.com
Abstract Parvovirus B19 (B19V) DNA persists lifelong in human tissues, but the cell type
harbouring it remains unclear. We here explore B19V DNA distribution in B, T and monocyte …

[HTML][HTML] Downregulation of EB virus miR-BART4 inhibits proliferation and aggressiveness while promoting radiosensitivity of nasopharyngeal carcinoma

Q Wu, T Han, X Sheng, N Zhang, P Wang - Biomedicine & …, 2018 - Elsevier
Objective This study aims to explore the role of Epstein-Barr virus (EBV) miR-BART4 in
occurrence and progression of nasopharyngeal carcinoma (NPC) and its effect on …

Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells

PM Hau, W Deng, L Jia, J Yang, T Tsurumi… - Journal of …, 2015 - Am Soc Microbiol
ABSTRACT Epstein-Barr virus (EBV), a type of oncogenic herpesvirus, is associated with
human malignancies. Previous studies have shown that lytic reactivation of EBV in latently …

[HTML][HTML] Follow-up after infectious mononucleosis in search of serological similarities with presymptomatic multiple sclerosis

D Jons, LP Berg, P Sundström, S Haghighi… - Multiple Sclerosis and …, 2021 - Elsevier
Background: A two-to three-fold increase in the risk of multiple sclerosis (MS) after infectious
mononucleosis (IM) has been observed in cohort and case control studies. However, this …

Epigenetic alterations in Epstein-Barr virus-associated diseases

HH Niller, F Banati, D Salamon, J Minarovits - Patho-Epigenetics of …, 2016 - Springer
Abstract Latent Epstein-Bar virus genomes undergo epigenetic modifications which are
dependent on the respective tissue type and cellular phenotype. These define distinct viral …

Human cytomegalovirus latency: targeting differences in the latently infected cell with a view to clearing latent infection

E Poole, M Wills, J Sinclair - New Journal of Science, 2014 - Wiley Online Library
Human cytomegalovirus (HCMV) is a human herpesvirus which causes little or no disease
in the immunocompetent. However, in immunocompromised individuals, neonates, or …