Background Despite the greater prevalence of familial hypercholesterolemia (FH) in
subjects with ischemic heart disease (IHD), premature IHD, and severe …

Objectives Heterozygous familial hypercholesterolaemia (FH) confers a significant risk for
premature cardiovascular disease (CVD). However, the estimated prevalence of FH varies …

Background Heterozygous familial hypercholesterolaemia is characterised by low cellular
uptake of LDL cholesterol, increased plasma LDL cholesterol concentrations, and premature …

Background—The prevalence of familial hypercholesterolemia (FH) is commonly reported
as 1 in 500. European reports suggest a higher prevalence; the US FH prevalence is …

Aims Ideally, familial hypercholesterolaemia (FH) is diagnosed by testing for mutations that
decrease the catabolism of low-density lipoprotein (LDL) cholesterol; however, genetic …

Familial hypercholesterolaemia is common in individuals who had a myocardial infarction at
a young age. As many as one in 200 people could have heterozygous familial …

Context: The diagnosis of familial hypercholesterolemia (FH) can be made using the Dutch
Lipid Clinic Network criteria. This employs the personal and family history of premature …

As atherosclerosis begins in childhood, early diagnosis and treatment of familial
hypercholesterolemia (FH) is considered necessary. The basic diagnosis of pediatric FH …

Objective To determine the efficacy of statin treatment on risk of coronary heart disease in
patients with familial hypercholesterolaemia. Design Cohort study with a mean follow-up of …

Familial Hypercholesterolemias: Prevalence, genetics, diagnosis and screening
recommendations from the National Lipid Association Expert Panel on Familial …