RNA-binding proteins in cancer: old players and new actors
RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …
combination of versatility of their RNA-binding domains with structural flexibility enables …
miRNA biogenesis and regulation of diseases: an updated overview
A Vishnoi, S Rani - MicroRNA Profiling: Methods and Protocols, 2022 - Springer
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and
translational repression by binding to the target mRNAs. Since it was discovered in 1993 …
translational repression by binding to the target mRNAs. Since it was discovered in 1993 …
MiRNA biogenesis and regulation of diseases: an overview
A Vishnoi, S Rani - MicroRNA profiling: Methods and protocols, 2017 - Springer
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and
translational repression by binding to target mRNAs. Since it was discovered in 1993 …
translational repression by binding to target mRNAs. Since it was discovered in 1993 …
[HTML][HTML] The somatic genomic landscape of glioblastoma
We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …
EVmiRNA: a database of miRNA profiling in extracellular vesicles
Extracellular vesicles (EVs), such as exosomes and microvesicles, acted as cell-to-cell
communication vectors and potential biomarkers for diseases. microRNAs (miRNAs) are the …
communication vectors and potential biomarkers for diseases. microRNAs (miRNAs) are the …
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism
P Bandopadhayay, LA Ramkissoon, P Jain… - Nature …, 2016 - nature.com
Angiocentric gliomas are pediatric low-grade gliomas (PLGGs) without known recurrent
genetic drivers. We performed genomic analysis of new and published data from 249 …
genetic drivers. We performed genomic analysis of new and published data from 249 …
MicroRNA biogenesis: regulating the regulators
EF Finnegan, AE Pasquinelli - Critical reviews in biochemistry and …, 2013 - Taylor & Francis
MicroRNAs (miRNAs) function as 21–24 nucleotide guide RNAs that use partial base-
pairing to recognize target messenger RNAs and repress their expression. As a large …
pairing to recognize target messenger RNAs and repress their expression. As a large …
MicroRNA turnover: when, how, and why
S Rüegger, H Großhans - Trends in biochemical sciences, 2012 - cell.com
MicroRNAs (miRNAs) are short (∼ 22 nucleotide) RNAs that are important for the regulation
of numerous biological processes. Accordingly, the expression of miRNAs is itself tightly …
of numerous biological processes. Accordingly, the expression of miRNAs is itself tightly …
[HTML][HTML] The RNA-binding protein QKI suppresses cancer-associated aberrant splicing
FY Zong, X Fu, WJ Wei, YG Luo, M Heiner, LJ Cao… - PLoS …, 2014 - journals.plos.org
Lung cancer is the leading cause of cancer-related death worldwide. Aberrant splicing has
been implicated in lung tumorigenesis. However, the functional links between splicing …
been implicated in lung tumorigenesis. However, the functional links between splicing …
[HTML][HTML] An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer
Alternative splicing of mRNA precursors represents a key gene expression regulatory step
and permits the generation of distinct protein products with diverse functions. In a genome …
and permits the generation of distinct protein products with diverse functions. In a genome …