Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre
MT Ringuet, A Koo, SGB Furness… - The Journal of …, 2023 - Wiley Online Library
Agonists of dopamine D2 receptors (D2R), 5‐hydroxytryptamine (5‐HT, serotonin) receptors
(5‐HTR) and ghrelin receptors (GHSR) activate neurons in the lumbosacral defecation …
(5‐HTR) and ghrelin receptors (GHSR) activate neurons in the lumbosacral defecation …
Alterations in descending brain-spinal pathways regulating colorectal motility in a rat model of Parkinson's disease
T Sawamura, N Yuki, K Aoki, K Horii… - American Journal …, 2024 - journals.physiology.org
Patients with Parkinson's disease (PD) often have constipation. It is assumed that a disorder
of the regulatory mechanism of colorectal motility by the central nervous system is involved …
of the regulatory mechanism of colorectal motility by the central nervous system is involved …
Lipopolysaccharide accelerates peristalsis by stimulating glucagon‐like peptide‐1 release from L cells in the rat proximal colon
H Nakamori, A Niimi, R Mitsui… - The Journal of …, 2024 - Wiley Online Library
Upon epithelial barrier dysfunction, lipopolysaccharide (LPS) stimulates glucagon‐like
peptide‐1 (GLP‐1) secretion from enteroendocrine L cells by activating Toll‐like receptor 4 …
peptide‐1 (GLP‐1) secretion from enteroendocrine L cells by activating Toll‐like receptor 4 …
Sexual dimorphism in prokinetic effects of a ghrelin agonist acting through the lumbosacral defecation center in rats
S Tsukamoto, T Sawamura, N Yuki, K Horii… - The Journal of …, 2024 - Springer
We investigated the effects of a centrally penetrant ghrelin agonist, RQ-00538053, on
colorectal motility in female rats in comparison with that in male rats. Intravenous …
colorectal motility in female rats in comparison with that in male rats. Intravenous …
Re-coding of G protein-coupled receptor signaling enables emergent cellular behavior
F Dehkhoda, MT Ringuet, EA Whitfield, K Mutunduwe… - bioRxiv, 2023 - biorxiv.org
All cells face the challenge of integrating multiple extracellular signals to produce relevant
physiological responses. Different combinations of G protein-coupled receptors, when co …
physiological responses. Different combinations of G protein-coupled receptors, when co …
[HTML][HTML] Colokinetic co-operation to control colorectal motility
KN Browning - The Journal of physiology, 2023 - pmc.ncbi.nlm.nih.gov
Colokinetic co-operation to control colorectal motility - PMC Skip to main content Here's how you
know Official websites use .gov A .gov website belongs to an official government organization …
know Official websites use .gov A .gov website belongs to an official government organization …
Regulation of colorectal motility by the central nervous system and defecation abnormalities: relation to constipation in Parkinson's disease
T Sawamura, K Horii, N Yuki, T Shiina… - The Autonomic Nervous …, 2024 - jstage.jst.go.jp
抄録 私たちは, ラットにおける中枢神経系による遠位結腸・直腸の運動調節機構について研究を
進めてきた. その結果, 下行性疼痛調節系を構成する神経核が脊髄より上位の排便中枢としての …
進めてきた. その結果, 下行性疼痛調節系を構成する神経核が脊髄より上位の排便中枢としての …
Central nervous system regulatory mechanisms of defecation
Y Shimizu, T Sawamura, N Yuki… - The Autonomic Nervous …, 2024 - jstage.jst.go.jp
抄録 私たちは, ラットにおける中枢神経系による大腸運動制御機構の解明に取り組んできた.
その結果, 大腸における侵害刺激が脊髄を経由して脳に伝えられ, 下行性疼痛調節経路の活性化 …
その結果, 大腸における侵害刺激が脊髄を経由して脳に伝えられ, 下行性疼痛調節経路の活性化 …