Antimicrobial peptides as therapeutic agents: Opportunities and challenges
M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
Pore formation in regulated cell death
The discovery of alternative signaling pathways that regulate cell death has revealed
multiple strategies for promoting cell death with diverse consequences at the tissue and …
multiple strategies for promoting cell death with diverse consequences at the tissue and …
The role of cell‐penetrating peptides in potential anti‐cancer therapy
M Zhou, X Zou, K Cheng, S Zhong, Y Su… - Clinical and …, 2022 - Wiley Online Library
Due to the complex physiological structure, microenvironment and multiple physiological
barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site …
barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site …
Pharmaceutical nanotechnology: Antimicrobial peptides as potential new drugs against WHO list of critical, high, and medium priority bacteria
CA Roque-Borda, PB Da Silva, MC Rodrigues… - European Journal of …, 2022 - Elsevier
Nanobiotechnology is a relatively unexplored area that has, nevertheless, shown relevant
results in the fight against some diseases. Antimicrobial peptides (AMPs) are …
results in the fight against some diseases. Antimicrobial peptides (AMPs) are …
TisB protein is the single molecular determinant underlying multiple downstream effects of ofloxacin in Escherichia coli
J Cayron, T Oms, T Schlechtweg, S Zedek… - Science …, 2024 - science.org
Bactericidal antibiotics can cause metabolic perturbations that contribute to antibiotic-
induced lethality. The molecular mechanism underlying these downstream effects remains …
induced lethality. The molecular mechanism underlying these downstream effects remains …
Antimicrobial mechanisms of biomaterials: from macro to nano
Overcoming the global concern of antibiotic resistance is one of the biggest challenges
faced by scientists today, and the key to tackling this issue of emerging infectious diseases is …
faced by scientists today, and the key to tackling this issue of emerging infectious diseases is …
Biophysical investigations elucidating the mechanisms of action of antimicrobial peptides and their synergism
A Marquette, B Bechinger - Biomolecules, 2018 - mdpi.com
Biophysical and structural investigations are presented with a focus on the membrane lipid
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …
The mechanisms of action of cationic antimicrobial peptides refined by novel concepts from biophysical investigations
C Aisenbrey, A Marquette, B Bechinger - Antimicrobial Peptides: Basics …, 2019 - Springer
Even 30 years after the discovery of magainins, biophysical and structural investigations on
how these peptides interact with membranes can still bear surprises and add new …
how these peptides interact with membranes can still bear surprises and add new …
Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis
The synthetic cyclic hexapeptide cWFW (cyclo (RRRWFW)) has a rapid bactericidal activity
against both Gram-positive and Gram-negative bacteria. Its detailed mode of action has …
against both Gram-positive and Gram-negative bacteria. Its detailed mode of action has …
[HTML][HTML] Small-angle scattering techniques for peptide and peptide hybrid nanostructures and peptide-based biomaterials
IW Hamley, V Castelletto - Advances in Colloid and Interface Science, 2023 - Elsevier
The use of small-angle scattering (SAS) in the study of self-assembly of peptides and
peptide conjugates (lipopeptides, polymer-peptide conjugates and others) is reviewed …
peptide conjugates (lipopeptides, polymer-peptide conjugates and others) is reviewed …