Thiophene‐containing compounds with antimicrobial activity

G Roman - Archiv der Pharmazie, 2022 - Wiley Online Library
Thiophene, as a member of the group of five‐membered heterocycles containing one
heteroatom, is one of the simplest heterocyclic systems. Many synthetic strategies allow the …

Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug …

GF Zha, SM Wang, KP Rakesh, SNA Bukhari… - European Journal of …, 2019 - Elsevier
The multidrug-resistant Staphylococcus aureus (MRSA) is one of the most prevalent human
pathogens involved in many minor to major disease burdens throughout the world. Inhibition …

Aryl fluorosulfate analogues as potent antimicrobial agents: SAR, cytotoxicity and docking studies

L Ravindar, SNA Bukhari, KP Rakesh… - Bioorganic …, 2018 - Elsevier
A series of aryl fluorosulfate analogues (1–37) were synthesized and tested for in vitro
antibacterial and antifungal studies, and validated by docking studies. The compounds 9 …

Synthesis, spectral characterization and X-ray crystal structure studies of 3-(benzo [d][1, 3] dioxol-5-yl)-5-(3-methylthiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1 …

K Kumara, AD Kumar, S Naveen, KA Kumar… - Journal of Molecular …, 2018 - Elsevier
Abstract A novel pyrazole derivative, 3-(benzo [d][1, 3] dioxol-5-yl)-5-(3-methylthiophen-2-yl)-
4, 5-dihydro-1H-pyrazole-1-carboxamide was synthesized and characterized by elemental …

Synthesis, characterization, crystal structure, Hirshfeld surface analysis, antioxidant properties and DFT calculations of a novel pyrazole derivative: ethyl 1-(2, 4 …

S Naveen, K Kumara, AD Kumar, KA Kumar… - Journal of Molecular …, 2021 - Elsevier
An effective route for the direct synthesis of substituted pyrazole through 3+ 2 annulation
method was described.(E)-ethyl 2-benzylidene-3-oxobutanoate was prepared from ethyl …

Design, synthesis and docking studies of novel 4-aminophenol-1, 2, 4-oxadiazole hybrids as apoptosis inducers against triple negative breast cancer cells targeting …

B Dhanalakshmi, BM Anil Kumar… - Journal of …, 2024 - Taylor & Francis
In our study, a series of novel 4-aminophenol benzamide-1, 2, 4-oxadiazole hybrid
analogues have been designed and synthesized by condensing 4-hydroxyphenyl …

Synthesis and Characterization of Cobalt (III) and Copper (II) Complexes of 2‐((E)‐(6‐Fluorobenzo [d] thiazol‐2‐ylimino) methyl)‐4‐chlorophenol: DNA Binding and …

K Savithri, BCV Kumar, HK Vivek… - International Journal …, 2018 - Wiley Online Library
A bidentate (N‐and O‐) imine‐based ligand (L1) and its metal complexes of types [CuII (L1)
2](C1),[CuII (L1)(Phen)](C2),[CoIII (L1) 2](C3), and [CoIII (L1)(Phen)](C4)(L1= 2‐((E)‐(6 …

Design and environmentally benign synthesis of novel thiophene appended pyrazole analogues as anti-inflammatory and radical scavenging agents: Crystallographic …

MG Prabhudeva, S Bharath, AD Kumar, S Naveen… - Bioorganic …, 2017 - Elsevier
Oxidative-stress induces inflammatory diseases and infections caused by drug-resistant
microbial strains are on the rise necessitating the discovery of novel small-molecules for …

Green synthesis of novel pyrazoline carbothioamides: A potent antimicrobial and antioxidant agents

DK Achutha, CB Vagish, N Renuka… - Chemical Data …, 2020 - Elsevier
Oxidative-stress induces inflammatory diseases caused by drug-resistant microbial stains
are on the increase necessitating the invention of novel small-molecules for intervention …

[PDF][PDF] 1, 2, 3-Triazoles: A review on current trends in synthetic and biological applications

P Sudeep, CB Vagish, AD Kumar, KA Kumar - J. Appl. Chem, 2020 - academia.edu
The chemistry of 1, 2, 3-triazoles gained much attention since the discovery by Pechmann,
since then several protocols have been developed for the synthesis of 1, 2, 3-triazoles, but …