Identification of apposite antagonist for androgen receptor in prostate cancer: an in silico study of fenugreek compounds

EA Olugbogi, OA Arobadade, DS Bodun… - Journal of …, 2023 - Taylor & Francis
Abstract Benign Prostate Cancer (BPC), a prevalent condition predominantly affecting
elderly males, manifests with voiding difficulties and urinary retention. A library of …

Exploring breast cancer treatment paradigms: innovative design, molecular docking and dynamic simulation of LOXL2 inhibitors

OA Baothman, MR Islam - Molecular Simulation, 2024 - Taylor & Francis
The impact of the LOXL2 enzyme on cell invasion and metastasis is significantly notable in
breast cancer (BC), making it a promising therapeutic target in cancer drug discovery …

Computational screening identifies depsidones as promising Aurora A kinase inhibitors: extra precision docking and molecular dynamics studies

MA Almogaddam, TH Shoaib, SGA Mohamed… - … Modeling Analysis in …, 2024 - Springer
The Aurora kinases play crucial roles in regulating mitotic progression and have implications
in various diseases, including cancer. In this study, we explored the potential of depsidone …