BACKGROUND Spermatozoa acquire their fertilizing ability and forward motility properties
during epididymal transit. Our knowledge of gamete physiology is based on studies …

Regenerative medicine and tissue engineering have seen unprecedented growth in the past
decade, driving the field of artificial tissue models towards a revolution in future medicine …

Purpose Cryopreservation of sperm is a widely used technique to maintain and protect the
fertility in various occasions such as infertility and malignancy treatments. This study aims to …

The process of freezing cells or tissues and depositing them in liquid nitrogen at–196° C is
called cryopreservation. Sub-zero temperature is not a physiological condition for cells and …

Cryopreservation is an expanding strategy to allow not only fertility preservation for
individuals who need such procedures because of gonadotoxic treatments, active duty in …

It is estimated that infertility affects 15–20% of couples and can arise from female or male
reproductive defects. Mouse models have ascribed roles to over 100 genes in the …

Cryodamage is a major problem in semen cryopreservation, causing changes in the levels
of proteins that influence the function and motility of spermatozoa. In this study, protein …

The cryopreservation of human spermatozoa has been an option for patients undergoing
chemo or radiotherapies since the late 1950s. Presently, there are different techniques for …

Recent technological advances provide new tools to manipulate cells and biological agents
in micro/nano-liter volumes. With precise control over small volumes, the cell …

Mitochondria-targeted antioxidants have great potential to counterbalance the generated
reactive oxygen species (ROS) because they cross the inner membrane of the mitochondria …