Endogenous retrovirus 3–history, physiology, and pathology

YY Bustamante Rivera, C Brütting, C Schmidt… - Frontiers in …, 2018 - frontiersin.org
Endogenous viral elements (EVE) seem to be present in all eukaryotic genomes. The
composition of EVE varies between different species. The endogenous retrovirus 3 (ERV3) …

CancerHERVdb: human endogenous retrovirus (HERV) expression database for human cancer accelerates studies of the retrovirome and predictions for HERV …

E Stricker, EC Peckham-Gregory… - Journal of …, 2023 - Am Soc Microbiol
In this study, we sought to create a database summarizing the expression of human
endogenous retroviruses (HERVs) in various human cancers. HERVs are suitable …

Human Endogenous Retrovirus (HERV)-K env Gene Knockout Affects Tumorigenic Characteristics of nupr1 Gene in DLD-1 Colorectal Cancer Cells

EJ Ko, MS Ock, YH Choi, JL Iovanna, S Mun… - International Journal of …, 2021 - mdpi.com
Human endogenous retroviruses (HERVs) are suggested to be involved in the development
of certain diseases, especially cancers. To elucidate the function of HERV-K Env protein in …

Expression of Human Endogenous Retrovirus env Genes in the Blood of Breast Cancer Patients

DW Rhyu, YJ Kang, MS Ock, JW Eo, YH Choi… - International journal of …, 2014 - mdpi.com
Human endogenous retroviruses (HERV) env proteins have been recently reported to be
significantly up-regulated in certain cancers. Specifically, mRNA and protein levels of HERV …

Human endogenous retrovirus env genes: Potential blood biomarkers in lung cancer

M Zare, S Mostafaei, A Ahmadi, SA Jamalkandi… - Microbial …, 2018 - Elsevier
Lung cancer, the leading cause of cancer mortality, needs urgent development of newly
qualified diagnostic and therapeutic biomarkers. Recently, Human Endogenous …

[HTML][HTML] Expression profiles of human endogenous retrovirus (HERV)-K and HERV-R Env proteins in various cancers

EJ Ko, KS Song, MS Ock, YH Choi, S Kim, HS Kim… - BMB …, 2021 - ncbi.nlm.nih.gov
The vertebrate genome contains an endogenous retrovirus that has been inherited from the
past millions of years. Although approximately 8% of human chromosomal DNA consists of …

ERVs-TLR3-IRF axis is linked to myelodysplastic syndrome pathogenesis

RTG de Oliveira, JVA Cordeiro, BF Vitoriano… - Medical Oncology, 2021 - Springer
Toll-like receptors are mutated or overexpressed in up to 50% of patients with
myelodysplastic syndrome (MDS). Endogenous retroviruses (ERV) trigger TLR3 leading to …

Molecular characterization of the peripheral airway field of cancerization in lung adenocarcinoma

JCJ Tsay, Z Li, TA Yie, F Wu, L Segal, AK Greenberg… - PloS one, 2015 - journals.plos.org
Field of cancerization in the airway epithelium has been increasingly examined to
understand early pathogenesis of non-small cell lung cancer. However, the extent of field of …

Elevation of human ERV3-1 env protein expression in colorectal cancer

SH Lee, YJ Kang, JO Jo, MS Ock, KW Baek… - Journal of clinical …, 2014 - jcp.bmj.com
DISCUSSION Interobserver variability has been described as a limitation of FISH, 3
especially with borderline cases presenting with 10–20% of ALK-positive cells. However, the …

Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer

KY Jeon, EJ Ko, YL Oh, H Kim, WK Eo, A Kim… - Genes & genomics, 2020 - Springer
Abstract Background Human endogenous retroviruses (HERVs) constitute around 8% of the
human genome and have important roles in human health and disease, including cancers …