[HTML][HTML] Nutraceutical properties of polyphenols against liver diseases

J Simón, M Casado-Andrés, N Goikoetxea-Usandizaga… - Nutrients, 2020 - mdpi.com
Current food tendencies, suboptimal dietary habits and a sedentary lifestyle are spreading
metabolic disorders worldwide. Consequently, the prevalence of liver pathologies is …

[HTML][HTML] Salvianolic acid C against acetaminophen-induced acute liver injury by attenuating inflammation, oxidative stress, and apoptosis through inhibition of the …

CT Wu, JS Deng, WC Huang, PC Shieh… - … Medicine and Cellular …, 2019 - hindawi.com
Acetaminophen (APAP) overdose is one of the most common causes of drug-induced acute
liver failure in humans. To investigate the hepatoprotective effect of salvianolic acid C (SAC) …

The dual role of immune response in acetaminophen hepatotoxicity: Implication for immune pharmacological targets

L Gong, L Liao, X Dai, X Xue, C Peng, Y Li - Toxicology Letters, 2021 - Elsevier
Acetaminophen (APAP), one of the most widely used antipyretic and analgesic drugs,
principally contributes to drug-induced liver injury when taken at a high dose. APAP-induced …

Integrated spatially resolved metabolomics and network toxicology to investigate the hepatotoxicity mechanisms of component D of Polygonum multiflorum Thunb

HY Jiang, HY Gao, J Li, TY Zhou, ST Wang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance The liver toxicity of Reynoutria multiflora (Thunb.)
Moldenke.(Polygonaceae)(Polygonum multiflorum Thunb, PM) has always attracted much …

[HTML][HTML] Hepatoprotective effect of baicalein against acetaminophen-induced acute liver injury in mice

HC Zhou, H Wang, K Shi, JM Li, Y Zong, R Du - Molecules, 2018 - mdpi.com
Baicalein (BAI), one of the main components of Scutellaria baicalensis Georgi, possesses
numerous pharmacological properties, including anti-cancer, anti-oxidative, anti-virus and …

[HTML][HTML] Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-κB, Keap1/Nrf2/HO-1, TLR4/PI3K …

WP Jiang, JS Deng, SS Huang, SH Wu, CC Chen… - Antioxidants, 2021 - mdpi.com
Liver damage induced by paracetamol overdose is the main cause of acute liver failure
worldwide. In order to study the hepatoprotective effect of Sanghuangporus sanghuang …

[HTML][HTML] Corilagin reduces acetaminophen-induced hepatotoxicity through MAPK and NF-κB signaling pathway in a mouse model

FC Liu, HP Yu, AH Chou, HC Lee… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Corilagin is a major active polyphenolic tannins extracted from Phyllanthus urinaria, an
important herb used in traditional medicine. Previous reports demonstrated that corilagin …

Selenium Ameliorates Acetaminophen-Induced Oxidative Stress via MAPK and Nrf2 Pathways in Mice

MC Indumathi, K Swetha, KV Abhilasha… - … Trace Element Research, 2024 - Springer
Overdose of acetaminophen (paracetamol), a widely used non-prescriptive analgesic and
antipyretic medication, is one of the main causes of drug-induced acute liver failure around …

Ginsenoside Rb1, A Major Saponin from Panax ginseng, Exerts Protective Effects Against Acetaminophen-Induced Hepatotoxicity in Mice

S Ren, J Leng, XY Xu, S Jiang, YP Wang… - The American Journal …, 2019 - World Scientific
Acute liver injury (ALI) induced by acetaminophen (APAP) is the main cause of drug-induced
liver injury. Previous reports indicated liver failure could be alleviated by saponins …

Chemical characterization and hepatoprotective effects of a standardized triterpenoid-enriched guava leaf extract

Y Li, J Xu, D Li, H Ma, Y Mu, D Zheng… - Journal of Agricultural …, 2021 - ACS Publications
Nutraceutical/pharmaceutical agents capable of maintaining redox and inflammation
homeostasis are considered as candidates for the prevention and/or treatment of liver …