Acoustofluidics, the integration of acoustics and microfluidics, is a rapidly growing research
field that is addressing challenges in biology, medicine, chemistry, engineering, and …

Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …

Metastasis formation is the main cause of cancer-related death in patients with solid
tumours. At the beginning of this process, cancer cells escape from the primary tumour to the …

Cell separation is a key step in many biomedical research areas including biotechnology,
cancer research, regenerative medicine, and drug discovery. While conventional cell sorting …

Abstract Organ-on-a-chip (OOC, organ chip) technology can closely simulate the human
microenvironment, synthesize organ-like functional units on a fluidic chip substrate, and …

Rare cells in blood, such as circulating tumor cells or fetal cells in the maternal circulation,
posses a great prognostic or diagnostic value, or for the development of personalized …

Metastasis is the main cause of tumor-related death, and the dispersal of tumor cells through
the circulatory system is a critical step in the metastatic process. Early detection and analysis …

Detection of circulating tumour cells (CTCs) plays a crucial role in the diagnosis of tumour
metastasis and evaluation of therapeutic effect on prognosis. The low number of the CTCs …

For more than 70 years, acoustic waves have been used to screen, diagnose, and treat
patients in hundreds of medical devices. The biocompatible nature of acoustic waves, their …

Enrichment of rare cells from peripheral blood has emerged as a means to enable
noninvasive diagnostics and development of personalized drugs, commonly associated with …