Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications

S Tambe, D Jain, Y Agarwal, P Amin - Journal of Drug Delivery Science …, 2021 - Elsevier
Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …

The technology for improving stability of nanosuspensions in drug delivery

W Guan, Y Ma, S Ding, Y Liu, Z Song, X Liu… - Journal of Nanoparticle …, 2022 - Springer
This review was devoted to the technology and approach for improving nanosuspensions
stability in drug delivery to retrieve the state-of-the-art nanosuspensions. The main content of …

[HTML][HTML] Pharmacokinetic control on the release of antimicrobial drugs from pH-responsive electrospun wound dressings

L Miranda-Calderon, C Yus, G Landa… - International Journal of …, 2022 - Elsevier
The acidic pH of healthy skin changes during wound healing due to the exposure of the
inner dermal and subcutaneous tissue and due to the potential colonization of pathogenic …

Smart mucoadhesive buccal chitosan/HPMC scaffold for sore throat: In vitro, ex vivo and pharmacokinetic profiling in humans

S Hanif, RM Sarfraz, MA Syed, A Mahmood… - Journal of Drug Delivery …, 2022 - Elsevier
Sore throat (ST) is exacerbated distress of throat which causes irritation during drinking and
swallowing. It is conventionally treated with throat soothing lozenges or spray for …

Modified glutinous rice starch-chitosan composite films for buccal delivery of hydrophilic drug

MT Soe, T Pongjanyakul, E Limpongsa… - Carbohydrate …, 2020 - Elsevier
The fabrication and characterization of ball-milling modified glutinous rice starch (MGRS):
chitosan (CS) composite films were demonstrated. Effect of CS ratios (2: 1, 1: 1, 1: 2 MGRS …

Fabrication of mucoadhesive films containing pharmaceutical ionic liquid and eudragit polymer using pressure-assisted microsyringe-type 3D printer for treating oral …

T Tagami, M Okamura, K Ogawa, T Ozeki - Pharmaceutics, 2022 - mdpi.com
Oral mucositis in the oral cavity, caused by radiation therapy and chemotherapy, requires
personalized care and therapy due to variations in the lesions of patients. In the present …

Assessment of Binary Agarose–Carbopol Buccal Gels for Mucoadhesive Drug Delivery: Ex Vivo and In Vivo Characterization

MA Syed, S Hanif, N Ain, HK Syed, AF Zahoor, IU Khan… - Molecules, 2022 - mdpi.com
Agarose (AG) is a naturally occurring biocompatible marine seaweed extract that is
converted to hydrocolloid gel in hot water with notable gel strength. Currently, its …

Lidocaine as eutectic forming drug for enhanced transdermal delivery of nonsteroidal anti-inflammatory drugs

HF Marei, MF Arafa, EA Essa… - Journal of Drug Delivery …, 2021 - Elsevier
Co-application of local anesthetics as lidocaine and nonsteroidal anti-inflammatory drugs
(NSAIDs) can enhance local analgesia. Co-formulation of lidocaine with NSAIDs can …

3D printing of patient-tailored SNEDDS-based suppositories of lidocaine

AT Chatzitaki, K Tsongas, EK Tzimtzimis… - Journal of Drug Delivery …, 2021 - Elsevier
Personalized drug delivery systems are considered an interesting perspective of the 3D
printing technology, with the potential to counterbalance the pharmacological and adverse …

Physicochemical Properties and Transdermal Absorption of a Flurbiprofen and Lidocaine Complex in the Non-Crystalline Form

Q Xu, T Furuishi, K Fukuzawa, E Yonemochi - Pharmaceutics, 2023 - mdpi.com
Amorphous drug formulations exploiting drug–drug interactions have been extensively
studied. This study aims to develop a transdermal system containing an amorphous complex …