In nature, the self-assembly of sequence-specific biopolymers into hierarchical structures
plays an essential role in the construction of functional biomaterials. To develop synthetic …

The rapid rise of multidrug-resistant (MDR) bacteria has once again caused bacterial
infections to become a global health concern. Antimicrobial peptides (AMPs), also known as …

Antimicrobial peptides (AMPs) are promising pharmaceutical candidates for the prevention
and treatment of infections caused by multidrug-resistant ESKAPE pathogens, which are …

In an attempt to find versatile and readily accessible coumarin scaffolds with a broad
spectrum of biomedical properties, seven bisimidazole–coumarin conjugates were …

The universal rise in the outbreak and fatality rates related to multidrug-resistant
microorganisms is a growing problem worldwide that necessitates the emergence of new …

The development of durable new antiviral therapies is challenging, as viruses can evolve
rapidly to establish resistance and attenuate therapeutic efficacy. New compounds that …

Peptides have unique characteristics that make them highly desirable as therapeutic agents.
The physicochemical and proteolytic stability profiles determine the therapeutic potential of …

Covering: 2009 up to August 2023 Prenyltransferases (PTs) are involved in the primary and
the secondary metabolism of plants, bacteria, and fungi, and they are key enzymes in the …

Hydroxycoumarins and their based conjugates revealed a wide-ranged biological activity
providing potential scaffolds to serve better in therapy. This work aims to synthesize six new …

The 3D structure and surface characteristics of proteins and peptides are crucial for
interactions with receptors or ligands and can be modified to some extent to modulate their …