Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Transmissible cancers are infectious parasitic clones that metastasize to new hosts, living
past the death of the founder animal in which the cancer initiated. We investigated the …

Populations of cancer cells are subject to the same core evolutionary processes as
asexually reproducing, unicellular organisms. Transmissible cancers are particularly striking …

Tasmanian devils have spawned two transmissible cancer lineages, named devil facial
tumor 1 (DFT1) and devil facial tumor 2 (DFT2). We investigated the genetic diversity and …

Siamese fighting (betta) fish are among the most popular and morphologically diverse pet
fish, but the genetic bases of their domestication and phenotypic diversification are largely …

Transmissible cancers are parasitic malignant cell lineages that have acquired the ability to
infect new hosts from the same species, or sometimes related species. First described in …

Conservation breeding programs aim to maintain 90% wild genetic diversity, but rarely
assess functional diversity. Here, we compare both genome-wide and functional diversity (in …

Although individual cancer cells are generally considered the Darwinian units of selection in
malignant populations, they frequently act as members of groups where fitness of the group …

Coevolution is common and frequently governs host–pathogen interaction outcomes.
Phenotypes underlying these interactions often manifest as the combined products of the …

Reproduction is one of the most energetically demanding life-history stages. As a result,
breeding individuals often experience trade-offs, where energy is diverted away from …