Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

A considerable number of human diseases have an inflammatory component, and a key
mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS) …

Phagocyte-derived reactive oxygen and nitrogen species are of crucial importance for host
resistance to microbial pathogens. Decades of research have provided a detailed …

Septic shock, the most severe complication of sepsis, is a deadly disease. In recent years,
exciting advances have been made in the understanding of its pathophysiology and …

Nitric oxide (NO) is recognized as a mediator and regulator of inflammatory responses. It
possesses cytotoxic properties that are aimed against pathogenic microbes, but it can also …

Propofol (2, 6-diisopropylphenol) is a potent intravenous hypnotic agent which is widely
used for the induction and maintenance of anesthesia and for sedation in the intensive care …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

The neuropathological correlates of encephalopathy and autonomic dysfuction in septic
shock are unclear. We performed post mortem analysis of 5 brain areas susceptible to …

Malaria causes an acute systemic human disease that bears many similarities, both
clinically and mechanistically, to those caused by bacteria, rickettsia, and viruses. Over the …

The vast majority of patients that are referred to a specialist hepatological centre suffer from
acute deterioration of their chronic liver disease. Yet, this entity of acute-on-chronic liver …