Microglia: agents of the CNS pro-inflammatory response
JA Rodríguez-Gómez, E Kavanagh… - Cells, 2020 - mdpi.com
The pro-inflammatory immune response driven by microglia is a key contributor to the
pathogenesis of several neurodegenerative diseases. Though the research of microglia …
pathogenesis of several neurodegenerative diseases. Though the research of microglia …
Emerging role of non-coding RNAs in neuroinflammation mediated by microglia and astrocytes
R Yang, B Yang, W Liu, C Tan, H Chen… - Journal of …, 2023 - Springer
Neuroinflammation has been implicated in the initiation and progression of several central
nervous system (CNS) disorders, including Alzheimer's disease, Parkinson's disease …
nervous system (CNS) disorders, including Alzheimer's disease, Parkinson's disease …
Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain
C Madore, Q Leyrolle, L Morel, M Rossitto… - Nature …, 2020 - nature.com
Abstract Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the
brain. Westernization of dietary habits in both developed and developing countries is …
brain. Westernization of dietary habits in both developed and developing countries is …
Reformulating pro-oxidant microglia in neurodegeneration
J García-Revilla, IM Alonso-Bellido… - Journal of Clinical …, 2019 - mdpi.com
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress
are central events. Recent genome-wide transcriptomic analyses of microglial cells under …
are central events. Recent genome-wide transcriptomic analyses of microglial cells under …
Roles of fatty acids in microglial polarization: evidence from in vitro and in vivo studies on neurodegenerative diseases
Microglial polarization to the M1 phenotype (classically activated) or the M2 phenotype
(alternatively activated) is critical in determining the fate of immune responses in …
(alternatively activated) is critical in determining the fate of immune responses in …
Impact of long-term supplementation with fish oil in individuals with non-alcoholic fatty liver disease: a double blind randomized placebo controlled clinical trial
K Cansanção, M Citelli, N Carvalho Leite… - Nutrients, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a chronic disease affecting up to 25% of the
population worldwide. n-3 long-chain polyunsaturated fatty acids (n-3 PUFA) have been …
population worldwide. n-3 long-chain polyunsaturated fatty acids (n-3 PUFA) have been …
Omega-3 polyunsaturated fatty acids alleviate early brain injury after traumatic brain injury by inhibiting neuroinflammation and necroptosis
Y Wu, J Zhang, X Feng, W Jiao - Translational Neuroscience, 2023 - degruyter.com
Presently, traumatic brain injury (TBI) is a leading contributor to disability and mortality that
places a considerable financial burden on countries all over the world. Docosahexaenoic …
places a considerable financial burden on countries all over the world. Docosahexaenoic …
DHA attenuated Japanese Encephalitis virus infection-induced neuroinflammation and neuronal cell death in cultured rat Neuron/glia
Abstract Japanese Encephalitis Virus (JEV) is a neurotropic virus and its Central Nervous
System (CNS) infection causes fatal encephalitis with high mortality and morbidity. Microglial …
System (CNS) infection causes fatal encephalitis with high mortality and morbidity. Microglial …
脊髓损伤再生修复中的问题与挑战
田婷, 李晓光 - 中国组织工程研究, 2021 - cjter.com
摘要背景: 脊髓损伤导致严重的感觉, 运动功能障碍, 反射异常以及自主神经功能紊乱.
目前脊髓损伤尚无有效的临床治疗措施. 近年来, 研究人员开发出多种新型治疗方案 …
目前脊髓损伤尚无有效的临床治疗措施. 近年来, 研究人员开发出多种新型治疗方案 …
Neuroprotective effect of the Nrf2/ARE/miRNA145-5p signaling pathway in the early phase of spinal cord injury
N Ebrahimy, N Gasterich, V Behrens, J Amini… - Life sciences, 2022 - Elsevier
Aims Spinal cord injury (SCI) is a debilitating neurological condition often associated with
chronic neuroinflammation and redox imbalance. Oxidative stress is one of the main …
chronic neuroinflammation and redox imbalance. Oxidative stress is one of the main …