Advances and challenges in uncovering cold tolerance regulatory mechanisms in plants

Y Ding, Y Shi, S Yang - New Phytologist, 2019 - Wiley Online Library
Contents Summary I. Introduction II. Cold stress and physiological responses in plants III.
Sensing of cold signals in plants IV. Messenger molecules involved in cold signal …

Cold signaling in plants: Insights into mechanisms and regulation

X Guo, D Liu, K Chong - Journal of integrative plant biology, 2018 - Wiley Online Library
To survive under cold temperatures plants must be able to perceive a cold signal and
transduce it into downstream components that induce appropriate defense mechanisms. In …

[HTML][HTML] TRP channels in thermosensation

M Kashio, M Tominaga - Current Opinion in Neurobiology, 2022 - Elsevier
The ability to sense external temperature is assumed by somatosensory neurons, in which
temperature information is converted to neural activity by afferent input to the central nervous …

[HTML][HTML] Regulation of body temperature by the nervous system

CL Tan, ZA Knight - Neuron, 2018 - cell.com
The regulation of body temperature is one of the most critical functions of the nervous
system. Here we review our current understanding of thermoregulation in mammals. We …

[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease

K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

SS Ranade, SH Woo, AE Dubin, RA Moshourab… - Nature, 2014 - nature.com
The sense of touch provides critical information about our physical environment by
transforming mechanical energy into electrical signals. It is postulated that mechanically …

Targeting thermogenesis in brown fat and muscle to treat obesity and metabolic disease

MJ Betz, S Enerbäck - Nature Reviews Endocrinology, 2018 - nature.com
Brown fat is emerging as an interesting and promising target for therapeutic intervention in
obesity and metabolic disease. Activation of brown fat in humans is associated with marked …

Structure of the cold-and menthol-sensing ion channel TRPM8

Y Yin, M Wu, L Zubcevic, WF Borschel, GC Lander… - Science, 2018 - science.org
Transient receptor potential melastatin (TRPM) cation channels are polymodal sensors that
are involved in a variety of physiological processes. Within the TRPM family, member 8 …

Regulation of pain and itch by TRP channels

C Moore, R Gupta, SE Jordt, Y Chen, WB Liedtke - Neuroscience bulletin, 2018 - Springer
Nociception is an important physiological process that detects harmful signals and results in
pain perception. In this review, we discuss important experimental evidence involving some …

The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia

K Song, H Wang, GB Kamm, J Pohle, FC Reis… - Science, 2016 - science.org
Body temperature homeostasis is critical for survival and requires precise regulation by the
nervous system. The hypothalamus serves as the principal thermostat that detects and …