A limited number of adult stem cells (SCs) maintain the homoestasis of different tissues
through the lifetime of the individual by generating differentiating daughters and renewing …

One of the most fascinating processes during nervous system development is the
establishment of stereotypic neuronal networks. An essential step in this process is the …

Neuronal polarization occurs shortly after mitosis. In neurons differentiating in vitro, axon
formation follows the segregation of growth-promoting activities to only one of the multiple …

The circadian timekeeping system of Drosophila functions from the first larval instar (L1)
onward but is not known to require the expression of clock genes in larvae. We show that …

Abstract The exocyst (Sec6/8) complex is necessary for secretion in yeast and has been
postulated to establish polarity by directing vesicle fusion to specific sites along the plasma …

Nicotinic acetylcholine receptors (nAChRs) are present in high density in insect nervous
tissue and are targeted by neonicotinoid insecticides. Improved understanding of the actions …

Although the ability to sense temperature is critical for many organisms, the underlying
mechanisms are poorly understood. Using the calcium reporter yellow cameleon 2.1 and …

Drosophila is an important model organism for investigating neural development, neural
morphology, neurophysiology, and neural correlates of behaviors. However, almost nothing …

1. The Drosophila gene Rdl (resistance to dieldrin) encodes a GABA receptor. An alanine‐to‐
serine mutation in this gene at residue 302 confers resistance to cyclodiene insecticides and …

Neuronal Ca2+ signals can affect excitability and neural circuit formation. Ca2+ signals are
modified by Ca2+ flux from intracellular stores as well as the extracellular milieu. However …