Properties of gluten intolerance: gluten structure, evolution, pathogenicity and detoxification capabilities

AV Balakireva, AA Zamyatnin Jr - Nutrients, 2016 - mdpi.com
Theterm gluten intolerance may refer to three types of human disorders: autoimmune celiac
disease (CD), allergy to wheat and non-celiac gluten sensitivity (NCGS). Gluten is a mixture …

Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology

H Hardy, J Harris, E Lyon, J Beal, AD Foey - Nutrients, 2013 - mdpi.com
Probiotics are beneficial microbes that confer a realistic health benefit on the host, which in
combination with prebiotics,(indigestible dietary fibre/carbohydrate), also confer a health …

Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology

JF Ludvigsson, JC Bai, F Biagi, TR Card, C Ciacci… - Gut, 2014 - gut.bmj.com
A multidisciplinary panel of 18 physicians and 3 non-physicians from eight countries
(Sweden, UK, Argentina, Australia, Italy, Finland, Norway and the USA) reviewed the …

Multiple common variants for celiac disease influencing immune gene expression

PCA Dubois, G Trynka, L Franke, KA Hunt… - Nature …, 2010 - nature.com
We performed a second-generation genome-wide association study of 4,533 individuals
with celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs …

Redox signaling in the gastrointestinal tract

S Pérez, R Taléns-Visconti, S Rius-Pérez… - Free Radical Biology …, 2017 - Elsevier
Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

Shared and distinct genetic variants in type 1 diabetes and celiac disease

DJ Smyth, V Plagnol, NM Walker… - … England Journal of …, 2008 - Mass Medical Soc
Background Two inflammatory disorders, type 1 diabetes and celiac disease, cosegregate in
populations, suggesting a common genetic origin. Since both diseases are associated with …

Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling

EG Severance, RH Yolken, WW Eaton - Schizophrenia research, 2016 - Elsevier
Autoimmunity, gastrointestinal (GI) disorders and schizophrenia have been associated with
one another for a long time. This paper reviews these connections and provides a context by …

The Microbiota–Gut–Brain Axis: Psychoneuroimmunological Insights

G Marano, M Mazza, FM Lisci, M Ciliberto, G Traversi… - Nutrients, 2023 - mdpi.com
There is growing interest in the role that the intestinal microbiota and the related
autoimmune processes may have in the genesis and presentation of some psychiatric …

Newly identified genetic risk variants for celiac disease related to the immune response

KA Hunt, A Zhernakova, G Turner, GAR Heap… - Nature …, 2008 - nature.com
Our genome-wide association study of celiac disease previously identified risk variants in
the IL2–IL21 region. To identify additional risk variants, we genotyped 1,020 of the most …

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

DA Van Heel, L Franke, KA Hunt, R Gwilliam… - Nature …, 2007 - nature.com
We tested 310,605 SNPs for association in 778 individuals with celiac disease and 1,422
controls. Outside the HLA region, the most significant finding (rs13119723; P= 2.0× 10− 7) …