Origins of specificity in protein-DNA recognition
Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …
processes. In this review, we provide a revised view of protein-DNA interactions that …
[HTML][HTML] Fuzzy complexes: Specific binding without complete folding
Specific molecular recognition is assumed to require a well-defined set of contacts and
devoid of conformational and interaction ambiguities. Growing experimental evidence …
devoid of conformational and interaction ambiguities. Growing experimental evidence …
MOLMOL: a program for display and analysis of macromolecular structures
R Koradi, M Billeter, K Wüthrich - Journal of molecular graphics, 1996 - Elsevier
MOLMOL is a molecular graphics program for display, analysis, and manipulation of three-
dimensional structures of biological macromolecules, with special emphasis on nuclear …
dimensional structures of biological macromolecules, with special emphasis on nuclear …
Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 Å resolution
Solvent binding in the nucleosome core particle containing a 147 base pair, defined-
sequence DNA is characterized from the X-ray crystal structure at 1.9 Å resolution. A single …
sequence DNA is characterized from the X-ray crystal structure at 1.9 Å resolution. A single …
[HTML][HTML] A novel mode of DNA recognition by a β‐sheet revealed by the solution structure of the GCC‐box binding domain in complex with DNA
The 3D solution structure of the GCC‐box binding domain of a protein from Arabidopsis
thaliana in complex with its target DNA fragment has been determined by heteronuclear …
thaliana in complex with its target DNA fragment has been determined by heteronuclear …
Homeodomain-DNA recognition
WJ Gehring, YQ Qian, M Billeter… - Cell, 1994 - Elsevier
Homeodomain-DNA Recognition Review Page 1 Cell, Vol. 79, 211-223, July 29, 1994, Copyright
0 1994 by Cell Press Homeodomain-DNA Recognition Review Waiter J. Gehring; Yan Giu …
0 1994 by Cell Press Homeodomain-DNA Recognition Review Waiter J. Gehring; Yan Giu …
PAX-6 IN DEVELOPMENT AND EVOLUTION
P Callaerts, G Halder, WJ Gehring - Annual review of …, 1997 - annualreviews.org
▪ Abstract Pax-6 is a member of the Pax gene class and encodes a protein containing a
paired domain and a homeodomain. The molecular characterization of Pax-6 genes from …
paired domain and a homeodomain. The molecular characterization of Pax-6 genes from …
[HTML][HTML] Functional specificity of a Hox protein mediated by the recognition of minor groove structure
The recognition of specific DNA-binding sites by transcription factors is a critical yet poorly
understood step in the control of gene expression. Members of the Hox family of …
understood step in the control of gene expression. Members of the Hox family of …
Detecting transient intermediates in macromolecular binding by paramagnetic NMR
Macromolecular complex formation is governed by two opposing constraints of specificity
and speed,. Kinetic,,, and theoretical considerations suggest that significant rate …
and speed,. Kinetic,,, and theoretical considerations suggest that significant rate …
[HTML][HTML] The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA
Telomeres, the nucleoprotein complexes at the ends of eukaryotic chromosomes, are
essential for chromosome stability. In the yeast S. cerevisiae, telomeric DNA is bound in a …
essential for chromosome stability. In the yeast S. cerevisiae, telomeric DNA is bound in a …