Complement and the regulation of T cell responses

EE West, M Kolev, C Kemper - Annual review of immunology, 2018 - annualreviews.org
The complement system is an evolutionarily ancient key component of innate immunity
required for the detection and removal of invading pathogens. It was discovered more than …

Complement, inflammation and thrombosis

E Rawish, M Sauter, R Sauter… - British Journal of …, 2021 - Wiley Online Library
A mutual relationship exists between immune activation and mechanisms of thrombus
formation. In particular, elements of the innate immune response such as the complement …

[HTML][HTML] Coagulopathies after vaccination against SARS-CoV-2 may be derived from a combined effect of SARS-CoV-2 spike protein and adenovirus vector-triggered …

R Kircheis - International journal of molecular sciences, 2021 - mdpi.com
Novel coronavirus SARS-CoV-2 has resulted in a global pandemic with worldwide 6-digit
infection rates and thousands of death tolls daily. Enormous efforts are undertaken to …

[HTML][HTML] Stable RNA markers for identification of blood and saliva stains revealed from whole genome expression analysis of time-wise degraded samples

D Zubakov, E Hanekamp, M Kokshoorn… - International journal of …, 2008 - Springer
Human body fluids such as blood and saliva represent the most common source of
biological material found at a crime scene. Reliable tissue identification in forensic science …

The anaphylatoxin C5a: Structure, function, signaling, physiology, disease, and therapeutics

M Ghosh, S Rana - International Immunopharmacology, 2023 - Elsevier
The complement system is one of the oldest known tightly regulated host defense systems
evolved for efficiently functioning cell-based immune systems and antibodies. Essentially …

Maggot excretions/secretions are differentially effective against biofilms of Staphylococcus aureus and Pseudomonas aeruginosa

MJA Van der Plas, GN Jukema, SW Wai… - Journal of …, 2008 - academic.oup.com
Objectives Lucilia sericata maggots are successfully used for treating chronic wounds. As
the healing process in these wounds is complicated by bacteria, particularly when residing …

Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2

H Lee, PL Whitfeld, CR Mackay - Immunology and cell biology, 2008 - Wiley Online Library
Complement component C5a is one of the most potent inflammatory chemoattractants and
has been implicated in the pathogenesis of numerous inflammatory diseases. C5a binds two …

[HTML][HTML] Complement in atherosclerosis: friend or foe?

WS Speidl, SP Kastl, K Huber, J Wojta - Journal of Thrombosis and …, 2011 - Elsevier
Atherosclerosis is a chronic inflammatory disease and the complement system plays a
central role in innate immunity. Increasing evidence exists that the complement system is …

[HTML][HTML] Inflammaging and complement system: a link between acute kidney injury and chronic graft damage

R Franzin, A Stasi, M Fiorentino, G Stallone… - Frontiers in …, 2020 - frontiersin.org
The aberrant activation of complement system in several kidney diseases suggests that this
pillar of innate immunity has a critical role in the pathophysiology of renal damage of …

C‐reactive protein: an in‐depth look into structure, function, and regulation

J Salazar, MS Martínez… - International …, 2014 - Wiley Online Library
Cardiovascular disease is the leading cause of morbidity and mortality in the adult
population worldwide, with atherosclerosis being its key pathophysiologic component …