Short peptide nanofiber biomaterials ameliorate local hemostatic capacity of surgical materials and intraoperative hemostatic applications in clinics

Z Yang, L Chen, J Liu, H Zhuang, W Lin… - Advanced …, 2023 - Wiley Online Library
Short designer self‐assembling peptide (dSAP) biomaterials are a new addition to the
hemostat group. It may provide a diverse and robust toolbox for surgeons to integrate wound …

A review of treatments for non-compressible torso hemorrhage (NCTH) and internal bleeding

C Hong, BD Olsen, PT Hammond - Biomaterials, 2022 - Elsevier
Non-compressible torso hemorrhage (NCTH) is associated with significant mortality in
preventable deaths, both in the field and in civilian settings. Current management strategies …

Microporous hemostatic sponge based on silk fibroin and starch with increased structural retentivity for contact activation of the coagulation cascade

J Lee, HN Choi, HJ Cha, YJ Yang - Biomacromolecules, 2023 - ACS Publications
Hemostatic agents with diverse forms and materials are necessitated to control excessive
bleeding to improve surgical site visibility during operation. The adequate use of hemostatic …

Antibacterial sponge for rapid noncompressible hemostatic treatment: spatiotemporal studies using a noninvasive model

P Sarkar, AS Pugazhendhi, M Coathup… - Biomaterials …, 2024 - pubs.rsc.org
Hemorrhage is one of the leading causes of preventable death. While minor injuries can be
treated mainly by conventional methods, deep and irregular wounds with profuse bleeding …

Graphene oxide reinforced hemostasis of gelatin sponge in noncompressible hemorrhage via synergistic effects

A Wenjing, F Du, Y He, B Wu, F Liu, Y Liu… - Colloids and Surfaces B …, 2022 - Elsevier
Effective hemostasis for noncompressible bleeding has been a key challenge because of
the deep, narrow, and irregular wounds. Swellable gelatin is an available hemostatic …

Recent advances in biopolymer-based hemostatic materials

M Mecwan, J Li, N Falcone, M Ermis… - Regenerative …, 2022 - academic.oup.com
Hemorrhage is the leading cause of trauma-related deaths, in hospital and prehospital
settings. Hemostasis is a complex mechanism that involves a cascade of clotting factors and …

Progress in injectable hydrogels for the treatment of incompressible bleeding: an update

X Wang, X Yang, Z Sun, X Guo, Y Teng… - … in Bioengineering and …, 2024 - frontiersin.org
Uncontrollable haemorrhage from deep, noncompressible wounds remains a persistent and
intractable challenge, accounting for a very high proportion of deaths in both war and …

Dual Burst and Sustained Release of p-Coumaric Acid from Shape Memory Polymer Foams for Polymicrobial Infection Prevention in Trauma-Related Hemorrhagic …

C Du, DA Fikhman, D Persaud… - ACS Applied Materials & …, 2023 - ACS Publications
Hemorrhage is the primary cause of trauma-related death. Of patients that survive,
polymicrobial infection occurs in 39% of traumatic wounds within a week of injury. Moreover …

Fast Recoverable Shape Memory Cryogels Engineered with Surfactant‐Stabilized Bubbles and Vermiculite for Non‐Compressible Hemostasis

B Wang, B Zhu, Y Liu, B Ren, Y Chen… - Advanced Functional …, 2024 - Wiley Online Library
Shape memory cryogels hold immense promise for non‐compressible hemostasis due to
their shape recovery after contacting with blood. However, there is still a lack of an easy way …

Nanofibrous chitin/Andrias davidianus skin secretion bioactive sponges with tunable biodegradation rates for bleeding wounds treatment

J Zhang, Q Wang, F Sefat, P Coates, W Zhang… - Chemical Engineering …, 2024 - Elsevier
Shape-memory sponges offer unique prospects for the treatment of uncontrollable bleeding.
However, the development of mechanically robust and bioactive shape-memory hemostatic …