The fact that not all individuals exposed to the same environmental risk factors develop
obesity supports the hypothesis of the existence of underlying genetic and epigenetic …

A healthy diet improves life expectancy and helps to prevent common chronic diseases such
as type 2 diabetes (T2D) and obesity. The mechanisms driving these effects are not fully …

Background One of the major challenges in obesity treatment is to explain the high
variability in the individual's response to specific dietary and physical activity interventions …

Background Studies demonstrate the impact of diet and physical activity on epigenetic
biomarkers, specifically DNA methylation. However, no intervention studies have examined …

Objective Obesity is driven by modifiable lifestyle factors whose effects may be mediated by
epigenetics. Therefore, we investigated lifestyle effects on blood DNA methylation in …

Background Studies suggest a correlation between excessive sedentary behavior,
insufficient physical activity, and an elevated likelihood of experiencing psychiatric disorder …

Neuroinflammation is a pathological hallmark of Alzheimer's disease (AD), characterized by
the stimulation of resident immune cells of the brain and the penetration of peripheral …

The risk of breast cancer increases with age, with the majority of women diagnosed with
breast cancer being postmenopausal. It has been estimated that 25–75% of women with …

Эпигенетические механизмы, опосредованно закодированные в геноме, изменяют
активность генов в ответ на воздействие образа жизни и факторов среды начиная с …

Background and aims To assess the associations of sedentary time, suppressor of cytokine
signaling (SOCS)-3 DNA methylation with type 2 diabetes mellitus (T2DM), and further …