Sažetak Estrogens have long been known as important regulators of the female
reproductive functions; however, our understanding of the role estrogens play in the human …

The field of cancer epigenetics is evolving rapidly on several fronts. Advances in our
understanding of chromatin structure, histone modification, transcriptional activity and DNA …

Environmental chemicals such as bisphenol A (BPA) are thought to contribute to
carcinogenesis through their endocrine-disrupting properties. Due to accumulating evidence …

Breast cancer is a heterogeneous disease affecting thousands of people every year.
Multiple factors are responsible in causing breast cancer while a number of treatment …

The heritability of B cell chronic lymphocytic leukemia (CLL) is relatively high; however, no
predisposing mutation has been convincingly identified. We show that loss or reduced …

The current study was designed to examine the actions of a model endocrine disruptor on
embryonic testis development and male fertility. Pregnant rats (F0) that received a transient …

Valproate (VPA) 1 has been used for decades in the treatment of epilepsy, and is also
effective as a mood stabilizer and in migraine therapy. It has been shown that VPA is also a …

Environmental exposures during sensitive windows of development can reprogram normal
physiologic responses and alter disease susceptibility later in life in a process known as …

The development of targeted therapies for antiestrogen-resistant breast cancer requires a
detailed understanding of its molecular characteristics. To further elucidate the molecular …

Testing for DNA methylation has potential in cancer screening. Most previous studies of
DNA methylation in cervical cancer used a candidate gene approach. The aim our study …