Functional metagenomics for enzyme discovery: challenges to efficient screening
T Uchiyama, K Miyazaki - Current opinion in biotechnology, 2009 - Elsevier
Metagenomics has emerged as an alternative approach to conventional microbial screening
that allows exhaustive screening of microbial genomes in their natural environments …
that allows exhaustive screening of microbial genomes in their natural environments …
The great screen anomaly—a new frontier in product discovery through functional metagenomics
DM Ekkers, MS Cretoiu, AM Kielak… - Applied microbiology and …, 2012 - Springer
Functional metagenomics, the study of the collective genome of a microbial community by
expressing it in a foreign host, is an emerging field in biotechnology. Over the past years, the …
expressing it in a foreign host, is an emerging field in biotechnology. Over the past years, the …
Changes in the proteome of Salmonella enterica serovar Thompson as stress adaptation to sublethal concentrations of thymol
Thymol is a natural biocide and component of some essential oils from herbs. Its inhibitory
effect on the growth of different microorganisms is well documented. The precise targets of …
effect on the growth of different microorganisms is well documented. The precise targets of …
Ribosomal protein S1 unwinds double-stranded RNA in multiple steps
X Qu, L Lancaster, HF Noller… - Proceedings of the …, 2012 - National Acad Sciences
The sequence and secondary structure of the 5′-end of mRNAs regulate translation by
controlling ribosome initiation on the mRNA. Ribosomal protein S1 is crucial for ribosome …
controlling ribosome initiation on the mRNA. Ribosomal protein S1 is crucial for ribosome …
Probing the relationship between Gram-negative and Gram-positive S1 proteins by sequence analysis
P Salah, M Bisaglia, P Aliprandi, M Uzan… - Nucleic acids …, 2009 - academic.oup.com
Escherichia coli ribosomal protein S1 is required for the translation initiation of messenger
RNAs, in particular when their Shine–Dalgarno sequence is degenerated. Closely related …
RNAs, in particular when their Shine–Dalgarno sequence is degenerated. Closely related …
Multiple activities of RNA-binding proteins S1 and Hfq
E Hajnsdorf, IV Boni - Biochimie, 2012 - Elsevier
In all organisms, RNA-binding proteins participate in modulating all the steps in the life cycle
of RNA, including transcription, folding, translation and turnover. In bacteria, RNA-binding …
of RNA, including transcription, folding, translation and turnover. In bacteria, RNA-binding …
Bioprospection of marine microorganisms: biotechnological applications and methods
HM Dionisi, M Lozada, NL Olivera - Revista argentina de …, 2012 - SciELO Argentina
Bioprospection of marine microorganisms: biotechnological applications and methods SciELO
- Scientific Electronic Library Online vol.44 número1 Predación selectiva de bacterias …
- Scientific Electronic Library Online vol.44 número1 Predación selectiva de bacterias …
Expression of heterologous sigma factors enables functional screening of metagenomic and heterologous genomic libraries
SM Gaida, NR Sandoval, SA Nicolaou, Y Chen… - Nature …, 2015 - nature.com
A key limitation in using heterologous genomic or metagenomic libraries in functional
genomics and genome engineering is the low expression of heterologous genes in …
genomics and genome engineering is the low expression of heterologous genes in …
Mining Novel Constitutive Promoter Elements in Soil Metagenomic Libraries in Escherichia coli
Although functional metagenomics has been widely employed for the discovery of genes
relevant to biotechnology and biomedicine, its potential for assessing the diversity of …
relevant to biotechnology and biomedicine, its potential for assessing the diversity of …
S1 ribosomal protein functions in translation initiation and ribonuclease RegB activation are mediated by similar RNA-protein interactions: an NMR and SAXS analysis
The ribosomal protein S1, in Escherichia coli, is necessary for the recognition by the
ribosome of the translation initiation codon of most messenger RNAs. It also participates in …
ribosome of the translation initiation codon of most messenger RNAs. It also participates in …