The CCAAT motif is one of the common promoter elements present in the proximal promoter
of numerous mammalian genes transcribed by RNA polymerase II. CBF (also called NF-Y …

Background The cytochrome P-450 superfamily is comprised of at least 27 distinct gene
families, 10 of which are found in mammals (Nebert et al., 1991; Gonzalez, 1990). P-450 …

Purpose There is a need for a simple, reliable staging system for multiple myeloma that can
be applied internationally for patient classification and stratification. Patients and Methods …

NF‐IL6 is a nuclear factor that specifically binds to an IL1‐responsive element in the IL‐6
gene. In this study the gene encoding NF‐IL6 has been cloned by direct screening of a …

Terminal differentiation of cultured 3T3-L1 fibroblasts to the adipogenic phenotype is
potently stimulated by dexamethasone (DEX) and methylisobutylxanthine (MIX). Previous …

Genetic Polymorphisms in the 5'-Flanking Region Change Transcriptional Regulation of the
Human Cytochrome P45011E1 Gene' Page 1 J. Biochem. 110, 559-565 (1991) Genetic …

CHOP (GADD153) is a mammalian nuclear protein that dimerizes with members of the
C/EBP family of transcription factors. Absent under normal growth conditions, CHOP is …

Mutations in the gene for the transcription factor hepatocyte nuclear factor (HNF) 1alpha
cause maturity-onset diabetes of the young (MODY) 3, a form of diabetes that results from …

Numerous studies have established the pivotal role of liver-enriched transcription factors in
organ development and cellular function, and there is conclusive evidence for transcription …

We analyzed a family of proteins from hepatoma cell nuclei that bind to interleukin-6
responsive elements (IL-6REs) of several acute-phase genes. This family is characterized …